Results 101 to 110 of about 364,066 (237)

Salvianolic Acid C Protects Against Hepatic Ischemia–Reperfusion Injury via Heat Shock Protein 90α‐Mediated Activation of the Phosphatidylinositol 3‐Kinase/Protein Kinase B Signaling Pathway

open access: yesPhytotherapy Research, EarlyView.
Salvianolic acid C (SaC) protects against hepatic ischemia–reperfusion injury (HIRI) by upregulating HSP90α and activating the PI3K/AKT pathway, thereby alleviating oxidative stress, inflammation, apoptosis, and necrosis. ABSTRACT Hepatic ischemia–reperfusion injury (HIRI) is a major challenge in liver surgery, and effective pharmacological ...
Pingping Qiao   +8 more
wiley   +1 more source

Iron deficiency in heart failure: Epidemiology, diagnostic criteria and treatment modalities

open access: yes
ESC Heart Failure, Volume 12, Issue 2, Page 723-726, April 2025.
Stephan von Haehling
wiley   +1 more source

Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy

open access: yesPhytotherapy Research, EarlyView.
This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi   +9 more
wiley   +1 more source

Disseminated cryptococcosis and hemochromatosis: clues to diagnosis

open access: yesAutopsy and Case Reports, 2021
Hepatic cirrhosis, diabetes mellitus and iron overload can each independently predispose to cryptococcosis. Hereditary hemochromatosis leads to all three of these predispositions.
Larry Nichols   +2 more
doaj  

Chemical and Biological Determinants of PEG‐Lipid Shedding From Therapeutic Nanoparticles

open access: yesSmall, EarlyView.
PEG‐lipids play a central role in governing lipid nanoparticle stability, targeting, and function. However, PEG‐lipids can “shed” from the nanoparticle surface in biological environments, with the extent and kinetics of shedding influenced by chemical and biological factors.
Ethan P. Cisneros   +2 more
wiley   +1 more source

Indices of iron homeostasis correlate with airway obstruction in an NHANES III cohort

open access: yesInternational Journal of COPD, 2017
Andrew J Ghio, Elizabeth D Hilborn Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, Chapel Hill, NC, USA Abstract: Cigarette smoking results in the accumulation of iron both systemically and locally ...
Ghio AJ, Hilborn ED
doaj  

Multi‐Scale 3D Printing of Magnetic Polymer Nanocomposites with Controlled Particle Dispersion and Hyperthermic Response

open access: yesSmall, EarlyView.
Dispersion of magnetic nanoflowers in trimethylolpropane ethoxylate triacrylate to generate photocurable nanocomposites is described. Particle dispersion provides processability and target AC‐field stimulated temperature increases. Complex (DLP) printed structures with submicron features are demonstrated, and the potential for stimulated release of ...
Eoin P. McKiernan   +9 more
wiley   +1 more source

Unsaturated Iron Binding capacity and Transferrin saturation are equally reliable in detection of HFE hemochromatosis

open access: yes, 2015
OBJECTIVE: Unsaturated iron binding capacity (UIBC) has been proposed as an inexpensive alternative to transferrin saturation for detection of hereditary hemochromatosis.
Tran, Huy Anh   +4 more
core   +1 more source

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

open access: yesSmart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy