Results 101 to 110 of about 5,482,088 (343)

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Genetic Studies of Sulfadiazine-resistant and Methionine-requiring \u3cem\u3eNeisseria\u3c/em\u3e Isolated From Clinical Material [PDF]

, 1967
Deoxyribonucleate (DNA) preparations were extracted from Neisseria meningitidis (four isolates from spinal fluid and blood) and N. gonorrhoeae strains, all of which were resistant to sulfadiazine upon primary isolation.
BROWN G. M., CATLIN B. W., CATLIN B. W., CATLIN B. W., CATLIN B. W., CAUTHEN S. E., DAVIS B. D., DAVIS B. D., DEMAIN A. L., DEMEREC M., E., DONALD I. J., DU VIGNEAUD V., W., EICKHOFF T. C., GRABOW W., HARRIS J. S., HATCH F. T., HOTCHKISS R. D., KAPLAN M. M., KATZEN H. M., KOHN H. I., LANDY M., LEDERBERG J., MILLAR J. W., OAKBERG E. F., PATO M. L., REYN A., REYN A., ROWBURY R. J., SICARD A. M., SINGER S., G., SMITH D. A., WILLCOX R. R., WINKLER K. C., WOLF B., WOODS D. D., WOODS D. D.   +35 more
core   +2 more sources

Review and Validation of Plant Gene Function Research Methods Bypassing Tissue Culture

Agronomy
The genetic transformation of plants has provided fundamental insights into plant biology. However, the genetic transformation systems for most horticultural plants remain incomplete.
Huanghuang Jiang, Suya Huang, Jiayi Wang, Deming Sun, Min Wang, Su Lin, Jinhua Liu, Kai Xu, Bei Liu, Haijie Ma   +9 more
doaj   +1 more source

Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome

Journal of Experimental Medicine, 2013
Characterization of the pattern of clonal evolution from CLL to RS, the genetic determinants of CLL transformation to RS, and the pathogenetic relationship between RS and classical non–CLL-associated de novo DLBCL.
G. Fabbri, Hossein Khiabanian, A. Holmes, Jiguang Wang, M. Messina, C. Mullighan, L. Pasqualucci, R. Rabadán, R. Dalla-Favera   +8 more
semanticscholar   +1 more source

Genetics and the Transformation of the Personal

Monash University Law Review, 2009
The shared nature of genetic information presents new challenges for legal understandings of the self. Within traditional legal discourses the individual is conceptualised as separate and autonomous. In contrast, the genetic individual is understood as inherently relational.
openaire   +2 more sources

Application of Developmental Regulators for Enhancing Plant Regeneration and Genetic Transformation

Plants
Establishing plant regeneration systems and efficient genetic transformation techniques plays a crucial role in plant functional genomics research and the development of new crop varieties.
Pingjun Xu, Yinxiao Zhong, Ang Xu, Bingshuang Liu, Yue Zhang, Anqi Zhao, Xiaoming Yang, Meiling Ming, Fuliang Cao, Fangfang Fu   +9 more
doaj   +1 more source

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

FEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling, Kodi Hunter, Celest W. S. Tay, Nicola T. Wood, Philip Cohen   +4 more
wiley   +1 more source

Genetic Transformation Among Azotobacter Species [PDF]

, 1977
Previous methods for genetic transformation in Azotobacter vinelandii have employed poorly defined genetic markers or crude DNA extracts. An improved transformation technique has been developed for use in Azotobacter.
Voth, Wayne H.
core   +1 more source

Genetic transformation of mouse embryos by microinjection of purified DNA.

Proceedings of the National Academy of Sciences of the United States of America, 1980
A recombinant plasmid composed of segments of herpes simplex virus and simian virus 40 viral DNA inserted into the bacterial plasmid pBR322 was microinjected into pronuclei of fertilized mouse oocytes.
J. Gordon, G. Scangos, D. J. Plotkin, J. Barbosa, F. Ruddle   +4 more
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source