Results 81 to 90 of about 4,162,309 (251)

Genetic transformation of the dinoflagellate chloroplast

eLife, 2019
Coral reefs are some of the most important and ecologically diverse marine environments. At the base of the reef ecosystem are dinoflagellate algae, which live symbiotically within coral cells.
Isabel C Nimmo, Adrian C Barbrook, Imen Lassadi, Jit Ern Chen, Katrin Geisler, Alison G Smith, Manuel Aranda, Saul Purton, Ross F Waller, R Ellen R Nisbet, Christopher J Howe   +10 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Maize Genome Editing and Genetic Transformation Platform

International audienceMaize genetic transformation is a critical tool for functional genomics, cellular biology, and crop improvement. It enables the study of gene function, protein localization, and supports genome editing approaches like CRISPR/Cas for
Widiez, Thomas, Rogowsky, Peter, Montes, Emilie   +2 more
core   +6 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Genetic transformation in Streptococcus pneumoniae: Molecular cloning and characterization of recP, a gene required for genetic recombination.

, 1988
Genetic transformation in Streptococcus pneumoniae: Molecular cloning and characterization of recP, a gene required for genetic ...
Dong-Kwon. Rhee (7971968)
core   +3 more sources

Advances in the Identification of Novel Urinary Biomarkers for Diabetic Kidney Disease

Journal of Diabetes Research
Diabetic kidney disease (DKD) is a major microvascular complication of diabetes and remains one of the leading causes of end-stage renal disease, significantly affecting patients' survival rates and quality of life.
Yujie Jin, Yan Ma, Yan Yao, Mengru Wang, Chunchen Ni, Shujuan Shang, Yongxin Cui, Xinyu Wang, Ye Ling, Yumeng Sun, Qirui Pei, Shiqiang Liu, Lizhuo Wang, Jialin Gao   +13 more
doaj   +1 more source

Review and Validation of Plant Gene Function Research Methods Bypassing Tissue Culture

Agronomy
The genetic transformation of plants has provided fundamental insights into plant biology. However, the genetic transformation systems for most horticultural plants remain incomplete.
Huanghuang Jiang, Suya Huang, Jiayi Wang, Deming Sun, Min Wang, Su Lin, Jinhua Liu, Kai Xu, Bei Liu, Haijie Ma   +9 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Application of Developmental Regulators for Enhancing Plant Regeneration and Genetic Transformation

Plants
Establishing plant regeneration systems and efficient genetic transformation techniques plays a crucial role in plant functional genomics research and the development of new crop varieties.
Pingjun Xu, Yinxiao Zhong, Ang Xu, Bingshuang Liu, Yue Zhang, Anqi Zhao, Xiaoming Yang, Meiling Ming, Fuliang Cao, Fangfang Fu   +9 more
doaj   +1 more source