Results 71 to 80 of about 1,028,732 (300)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Horizontal DNA transfer mechanisms of bacteria as weapons of intragenomic conflict [PDF]

, 2016
Horizontal DNA transfer (HDT) is a pervasive mechanism of diversification in many microbial species, but its primary evolutionary role remains controversial.
A Adams, A Adams, AB Dalia, AI Khan, B Martin, BJ Haijema, BR Levin, C Boutry, C Buchrieser, C Camacho, C Canchaya, C Chewapreecha, C Fraser, C Johnston, C Johnston, C Johnston, Christophe Fraser, Christopher Wymant, CS Wylie, D Dubnau, D Hyatt, DA Baltrus, DA Caugant, DA Higgins, DA Morrison, DA Morrison, DE Fouts, DJP Engelmoer, E Borezee, E Szathmáry, E V Pestova, E Zaccaria, EA Campbell, EJ Feil, EJ Gaasbeek, EJ Gaasbeek, EP Rocha, ES Antonova, F Ginetti, F Griffith, F Liu, GG Wilson, GJ Stewart, GM Süel, GW Goldberg, H Bagci, H Bernstein, H Deveau, H Li, H Maamar, H Muller, H Ochman, H Tong, H-H Chou, HC Neu, I Chen, I Mortier-Barriere, I Mortier-Barrière, J Bondy-Denomy, J Guglielmini, J Majewski, J Majewski, J-P Claverys, JA Lanie, JA Londoño-Vallejo, JA Mongold, JC Lefevre, JC Mell, JH Stuy, JJ Sakamoto, JK Setlow, JM Auchtung, JM Musser, JM Smith, JM Smith, JO McInerney, JP Claverys, JP Claverys, JT Simpson, JW Beaber, K Turgay, KS Makarova, KT Konstantinidis, L Attaiech, L Fontaine, L Van Valen, L-M Bobay, LP Macfadyen, LS Frost, LS Håvarstein, LS Håvarstein, M Berge, M Boetzer, M Del Grosso, M Prudhomme, M Ramirez, MA Hoelzer, ME Kahn, MF Wojciechowski, MJ Lopez-Sanchez, ML Gwinn, MR Oggioni, MS Dorer, MTG Holden, Nicholas J. Croucher, Nick H. Barton, NJ Croucher, NJ Croucher, NJ Croucher, NJ Croucher, NJ Croucher, NJ Croucher, NJ Croucher, NJ Croucher, NJ Croucher, NJ Croucher, O Johnsborg, OE Cornejo, OH Ambur, OT Avery, P Glaser, P Jorth, P Luo, PA Levin, Paul Turner, PJ Johnsen, R Davidoff-Abelson, R Edgar, R Mostowy, RA Fisher, Rafal Mostowy, RE Michod, RE Yasbin, RJ Redfield, RJ Redfield, RJ Redfield, RJ Redfield, RJ Redfield, RJ Redfield, RK Aziz, RP Novick, S Lacks, SA McMahon, SB Beres, SE Finkel, SJ Labrie, SP Otto, Stephen D. Bentley, T Carver, T Nozawa, U Munoz-Najar, WA Sweetman, WJ Kent, X Charpentier, X Charpentier, X Didelot, Y Li, Z Zhou   +157 more
core   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Genetic resources and genetic transformation in bermudagrass – a review

Biotechnology & Biotechnological Equipment, 2018
Bermudagrass is widely distributed as a warm-season turf and forage grass in the temperate and tropical zones around the world. Its strong vegetative reproduction and ability to withstand drought make it an ideal species as a most used warm-season forage
Shilian Huang, Chen Wang, Junsong Liang
doaj   +1 more source

Efficiency of Genetic Transformation Via Pollen-Tube Pathway of Jatropha (Jatropha Curcas L.) Based on Histochemical and Molecular Analysis [PDF]

, 2017
The genetic transformation via pollen-tube pathway is an alternative method to overcome the constraints imposed by genotype specificity in transformation and regeneration in jatropha (Jatropha curcas L.) tissue culture.
Ardie, S. W. (Sintho), Purwoko, B. S. (Bambang), Santoso, T. J. (Tri), Trikoesoemaningtyas, A. (and), Zainudin, A. (Agus)   +4 more
core  

Tomato: a crop species amenable to improvement by cellular and molecular methods [PDF]

, 1989
Tomato is a crop plant with a relatively small DNA content per haploid genome and a well developed genetics. Plant regeneration from explants and protoplasts is feasable which led to the development of efficient transformation procedures.
A. Crossway, A. Guri, A. Hoekema, A. Kinshara, A. Morgan, A. Zelcer, A.H. Paterson, A.J. Framond De, A.L. Phillips, A.L. Phillips, A.R. Krol Van der, B. Baker, B. Baker, B. Hause, B. McClintock, B. Piechulla, B.A. Levenko, B.D. Harrison, B.L. Ward, B.P. Moens, B.R. Thomas, B.R. Thomas, B.S. Gill, B.S. Landry, B.S. Landry, B.S. Landry, C. Chang, C. Pieterse, C. Waldron, C.D. Riggs, C.E. Vallejos, C.E. Vallejos, C.J.S. Smith, C.M. Rick, C.M. Rick, C.M. Rick, C.M. Rick, C.M. Rick, C.M. Rick, C.M. Rick, C.M. Rick, C.M. Smith, C.P. Meredith, D. Boer De, D. Botstein, D. Shah, D. Zamir, D. Zamir, D. Zamir, D.A. Evans, D.A. Evans, D.M. Barker, D.M. Lonsdale, D.P. Barlow, D.W. Barton, D.W. Galbraith, E. Haute Van, E. Pichersky, E.A. Frankenberger, E.A. Frankenberger, E.A. Shahin, E.A. Shahin, E.C. Tigchelaar, F.J. Zapata, G. Gavazzi, G. Melchers, G. Schweizer, G.S. Khush, G.S. Khush, H.P. Mühlbach, I. Negrutiu, I.M. Greenblat, J. Botterman, J. Haseloff, J. Hille, J. Hille, J. Paszkowski, J. Phillips, J. Wijbrandi, J.D. Palmer, J.D. Palmer, J.D. Palmer, J.D. Palmer, J.F. Gusella, J.F. Gusella, J.F. Shepard, J.G. Atherton, J.H. Hawkes, J.I. Yoder, J.J. Fillatti, J.L. Bennetzen, J.M. van Montagu Schell, J.S. Beckmann, J.S. Beckmann, J.W. Maxon-Smith, J.W. Verna De, Jacoues Hille, K. Ohyama, K. Shinozaki, K. Umesono, K.A. Darden, K.K. Kartha, L. Herrera-Estrella, L. Herrera-Estrella, L. Marton, L.A. Miki, L.P. Hosticka, L.W. Handley, M. Block De, M. Buiatti, M. Buiatti, M. Cuozzo, M. Jongsma, M. Koornneef, M. Koornneef, M. Mutschler, M. S. Ramanna, M. Sibi, M. Soller, M. Vaeek, M. Wallroth, M. Ziv, M.A. O'Connell, M.A. O'Connell, M.A. O'Connell, M.A. O'Connell, M.A. Sluys Van, M.A. Stevens, M.A. Stevens, M.D. Bennett, M.L.M.C. Tan, M.L.M.C. Tan, M.R. Hanson, M.S. Ramanna, M.S. Ramanna, M.S. Ramanna, M.W. Bevan, M.W. Ganal, M.Y. Menzel, Maarten Koornneef, N.A. Zagorska, N.D. Young, N.D. Young, N.E. Tumer, N.V. Federoff, P. Little, P. Zambryski, P.E. McClean, P.F. Ambros, P.G. Smith, P.J.M. Elzen Van den, P.J.M. Elzen Van den, P.M. Gresshoff, Pim Zabel, R. Bernatzky, R. Bernatzky, R. Ecochard, R. Hain, R. Niedz, R.A. Bressan, R.A.J. Daelen Van, R.B. Flavell, R.B. Horsch, R.D. Locky, R.D. Shillito, R.S. Nelson, R.T. Fraley, S. Dellaporta, S. McCormick, S. Ohki, S.D. Tanksley, S.D. Tanksley, S.D. Tanksley, S.D. Tanksley, S.D. Tanksley, S.D. Tanksley, St.G. Rogers, T. Helentjaris, T. Helentjaris, T. Helentjaris, T.C. Osborn, T.L. Adams, T.M. Klein, U. Wienand, V. Padmanabhan, V.A. Hilder, W. Gottschalk, W. Gruissem, W.L. Gerlach, W.R. Sharp, Y.S. Chyi, Z. Koukolikova-Nicola, Z. Tabaeizadeh   +192 more
core   +3 more sources

Genetic transformation of Sorghum bicolor [PDF]

Physiology and Molecular Biology of Plants, 2009
Great millet (Sorghum bicolor (L.) Moench) is cultivated across the world for food and fodder. It is typically grown in semiarid regions that are not suitable for cultivation of other major cereals. Sexual incompatibility and shortage of available genes in germplasm to combat biotic and abiotic stresses resulted in marginalized yields of this crop ...
V, Girijashankar, V, Swathisree
openaire   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Genetics of Follicular Lymphoma Transformation

Cell Reports, 2014
Follicular lymphoma (FL) is an indolent disease, but 30-40% of cases undergo histologic transformation to an aggressive malignancy, typically represented by diffuse large B cell lymphoma (DLBCL). The pathogenesis of this process remains largely unknown.
PASQUALUCCI, Laura, Khiabanian H, Fangazio M, Vasishtha M, Messina M, Holmes AB, Ouillette P, Trifonov V, Rossi D, Tabbò F, Ponzoni M, Chadburn A, Murty VV, Bhagat G, Gaidano G, Inghirami G, Malek SN, Rabadan R, Dalla Favera R.   +18 more
openaire   +6 more sources