Results 101 to 110 of about 6,507,008 (334)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Ground-State Preparation and Energy Estimation on Early Fault-Tolerant Quantum Computers via Quantum Eigenvalue Transformation of Unitary Matrices

, 2022
Yulong Dong, Lin Lin, Yu Tong
openalex   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Critical sustainability events and perceived roles of academic leaders at a leading university in sustainability: CIT case study

Discover Sustainability
This case study explores the perceived roles of academic leaders in critical sustainability events at a leading university in sustainability—the University of Auckland (UoA). The UoA was selected because of its high position in the Times Higher Education
Anete Veidemane, Daniela Craciun, Barend van der Meulen   +2 more
doaj   +1 more source

Transformational Logic and Social Transformation

WISDOM, 2016
This paper presents the basics of Academic Brutian’s conception of transformational logic and the application of its methodological means to the study of optimal ways for transforming former socialist system of Armenia into social state in the frame of capitalist free market economy.
openaire   +3 more sources

Mineral phase transformation in coal gangue by high temperature calcination and high-efficiency separation of alumina and silica minerals

, 2021
Mingzhuang Xie, Fengqin Liu, Hongliang Zhao, Chaoyang Ke, Zhiqian Xu   +4 more
openalex   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Burden on the burdened: tuberculosis among Scheduled Tribes and non-Scheduled Tribes in constitutionally protected Scheduled and non-Scheduled areas of India

Infectious Diseases of Poverty
Background India accounts for over a quarter of the global tuberculosis (TB) burden. Among the most affected are India’s Scheduled Tribes (STs) communities, experiencing a disproportionately higher TB prevalence compared to non-STs.
Nishikant Singh, Sudheer Kumar Shukla, Ritam Dubey, Pratheeba John, Rituparna Sengupta, Ritesh Ranjan Pushkar, Navin Singh, Prince Chugh, Nishant Yadav, Rajeev Sadanandan   +9 more
doaj   +1 more source

Elementary derivations of identities for bilateral basic hypergeometric series

, 2000
We give elementary derivations of several classical and some new summation and transformation formulae for bilateral basic hypergeometric series. For purpose of motivation, we review our previous simple proof ("A simple proof of Bailey's very-well-poised
Schlosser, M.
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source