Results 41 to 50 of about 6,507,008 (334)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

A Reciprocal Transformation for the Constant Astigmatism Equation [PDF]

open access: yes, 2014
We introduce a nonlocal transformation to generate exact solutions of the constant astigmatism equation $z_{yy} + (1/z)_{xx} + 2 = 0$. The transformation is related to the special case of the famous B\"acklund transformation of the sine-Gordon equation ...
Hlaváč, Adam, Marvan, Michal
core   +1 more source

Monad transformers as monoid transformers

open access: yesTheoretical Computer Science, 2010
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
JASKELIOFF M, MOGGI, EUGENIO
openaire   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Food industry perspectives on potential policies targeting unhealthy food and beverage price promotions in Australian supermarkets

open access: yesBMC Public Health, 2022
Current supermarket price promotions are likely to encourage unhealthy diets, leading some governments to recently endorse restrictions on price promotions for unhealthy food and beverages.
Lily Grigsby-Duffy   +3 more
doaj   +1 more source

Stress-Induced Phase Transformations in Shape-Memory Polycrystals [PDF]

open access: yes, 2008
Shape-memory alloys undergo a solid-to-solid phase transformation involving a change of crystal structure. We examine model problems in the scalar setting motivated by the situation when this transformation is induced by the application of stress in a ...
Bhattacharya, Kaushik   +1 more
core   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Assessing the financial burden of multimorbidity among patients aged 30 and above in India

open access: yesBMC Health Services Research
Background Multimorbidity is associated with significant out-of-pocket expenditures (OOPE) and catastrophic health expenditure (CHE), especially in low- and middle-income countries like India.
Sudheer Kumar Shukla   +5 more
doaj   +1 more source

Appell Transformation and Canonical Transforms [PDF]

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2011
The interpretation of the optical Appell transformation, as previously elaborated in relation to the free-space paraxial propagation under both a rectangular and a circular cylindrical symmetry, is reviewed. Then, the caloric Appell transformation, well known in the theory of heat equation, is shown to be amenable for a similar interpretation involving
openaire   +5 more sources

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

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