Results 61 to 70 of about 7,948,396 (393)

Association between the school physical activity environment, measured and self-reported student physical activity and active transport behaviours in Victoria, Australia

International Journal of Behavioral Nutrition and Physical Activity, 2021
Background Environments within schools including the physical, social-cultural and policy/practice environments have the potential to influence children’s physical activity (PA) behaviours and weight status.
Nicholas Crooks, Laura Alston, Melanie Nichols, Kristy A. Bolton, Steven Allender, Penny Fraser, Ha Le, Joanne Bliss, Claire Rennie, Liliana Orellana, Claudia Strugnell   +10 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Nucleosomes affect local transformation efficiency [PDF]

, 2012
Genetic transformation is a natural process during which foreign DNA enters a cell and integrates into the genome. Apart from its relevance for horizontal gene transfer in nature, transformation is also the cornerstone of today's recombinant gene ...
Aslankoohi, Elham, Marchal, Kathleen, Sanchez-Rodriguez, Aminael, Sun, Hong, van der Zande, Elisa, Verstrepen, Kevin J, Voordeckers, Karin   +6 more
core   +2 more sources

Neutrophil membrane engineered HucMSC sEVs alleviate cisplatin-induced AKI by enhancing cellular uptake and targeting

Journal of Nanobiotechnology, 2022
Human umbilical cord mesenchymal stem cells-derived small extracellular vesicles (hucMSC-sEVs) have been demonstrated as a therapeutic agent to prevent and treat cisplatin-induced acute kidney injury (AKI).
Peipei Wu, Yuting Tang, Can Jin, Min Wang, Linli Li, Zhong Liu, Hui Shi, Zixuan Sun, Xiaomei Hou, Wenya Chen, Wenrong Xu, Hui Qian   +11 more
doaj   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Local to global policy as a catalyst for change: key messages [PDF]

, 2019
Feeding and nourishing a growing and changing global population in the face of rising numbers of chronically hungry people, slow progress on malnutrition, environmental degradation, systemic inequality, and the dire projections of climate change ...
Antonelli, Marta, Chatrchyan, Allison, Clayton, Terry, Fanzo, Jessica, Gonsalves, Julian, Matthews, Alan, Nierenberg, Danielle, Rawe, Tonya, Zurek, Monika   +8 more
core  

Challenges for remote patient monitoring programs in rural and regional areas: a qualitative study

BMC Health Services Research
Background Access to healthcare significantly influences health outcomes, and rural, regional and remote populations face greater challenges in accessing healthcare than urban populations.
Joel Fossouo Tagne, Kara Burns, Teresa O’Brein, Wendy Chapman, Portia Cornell, Kit Huckvale, Ishaan Ameen, Jaclyn Bishop, Alison Buccheri, Jodie Reid, Anna Wong Shee, Marc Budge, Catherine E. Huggins, Anna Peeters, Olivia Metcalf   +14 more
doaj   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

Group physical therapy for knee osteoarthritis: protocol for a hybrid type III effectiveness-implementation trial

Implementation Science Communications, 2023
Background Knee osteoarthritis (OA) is a leading cause of chronic pain and disability and one of the most common conditions treated in outpatient physical therapy (PT).
Sara Webb, Connor Drake, Cynthia J. Coffman, Caitlin Sullivan, Nina Sperber, Matthew Tucker, Leah L. Zullig, Jaime M. Hughes, Brystana G. Kaufman, John A. Pura, Livia Anderson, Susan N. Hastings, Courtney H. Van Houtven, Lauren M. Abbate, Helen Hoenig, Lindsay A. Ballengee, Virginia Wang, Kelli D. Allen   +17 more
doaj   +1 more source

Knowledge-Based Intelligent Text Simplification for Biological Relation Extraction

Informatics, 2023
Relation extraction from biological publications plays a pivotal role in accelerating scientific discovery and advancing medical research. While vast amounts of this knowledge is stored within the published literature, extracting it manually from this ...
Jaskaran Gill, Madhu Chetty, Suryani Lim, Jennifer Hallinan   +3 more
doaj   +1 more source