Results 1 to 10 of about 148,688 (144)

Genetics of Follicular Lymphoma Transformation

open access: goldCell Reports, 2014
Follicular lymphoma (FL) is an indolent disease, but 30%–40% of cases undergo histologic transformation to an aggressive malignancy, typically represented by diffuse large B cell lymphoma (DLBCL). The pathogenesis of this process remains largely unknown.
Laura Pasqualucci   +18 more
doaj   +2 more sources

Increasing of Amylopectin in Tetraploid Potato Desiree Cultivar (Solanum tuberosum L.) Via CRISPR/Cas9 [PDF]

open access: yesArab Universities Journal of Agricultural Sciences, 2023
Potato tuber starch characteristic is influenced by the ratio of amylose to amylopectin, which is affected by the granule-bound starch synthase (GBSS) gene.
Nermin Ali   +5 more
doaj   +1 more source

Decreasing of Monosaccharide Contents Resulted From Cold- Induced Sweetening in Tetraploid Potato (Solanum tuberosum L.) Using Genome Editing [PDF]

open access: yesArab Universities Journal of Agricultural Sciences, 2023
Worldwide, potato (Solanum tuberosum L.) is one of the most essential agro-economically food crops. To ensure its presence throughout the year for food processors and to extend its shelf life, it should be stored in cold temperatures.
Sally Hassan   +5 more
doaj   +1 more source

Gastrodin ameliorates the lipopolysaccharide-induced neuroinflammation in mice by downregulating miR-107-3p

open access: yesFrontiers in Pharmacology, 2022
Background: Neuroinflammation plays a pivotal role in the pathogenesis of Central Nervous System (CNS) diseases. The phenolic glucoside gastrodin (GAS), has been known to treat CNS disorders by exerting anti-inflammatory activities.
Jin-Jin Song   +17 more
doaj   +1 more source

Interactions Between Intestinal Microbiota and Neural Mitochondria: A New Perspective on Communicating Pathway From Gut to Brain

open access: yesFrontiers in Microbiology, 2022
Many studies shown that neurological diseases are associated with neural mitochondrial dysfunctions and microbiome composition alterations. Since mitochondria emerged from bacterial ancestors during endosymbiosis, mitochondria, and bacteria had analogous
Yao Zhu   +6 more
doaj   +1 more source

Insights into the genetic influences of the microbiota on the life span of a host

open access: yesFrontiers in Microbiology, 2023
Escherichia coli (E. coli) mutant strains have been reported to extend the life span of Caenorhabditis elegans (C. elegans). However, the specific mechanisms through which the genes and pathways affect aging are not yet clear.
Fang Zhang   +11 more
doaj   +1 more source

Transcriptome analysis of activated charcoal-induced growth promotion of wheat seedlings in tissue culture

open access: yesBMC Genetics, 2020
Background Activated charcoal (AC) is highly adsorbent and is often used to promote seedling growth in plant tissue culture; however, the underlying molecular mechanism remains unclear.
Fu-shuang Dong   +9 more
doaj   +1 more source

Establishment of a Genetic Transformation System in Guanophilic Fungus Amphichorda guana

open access: yesJournal of Fungi, 2021
Fungi from unique environments exhibit special physiological characters and plenty of bioactive natural products. However, the recalcitrant genetics or poor transformation efficiencies prevent scientists from systematically studying molecular biological ...
Min Liang   +5 more
doaj   +1 more source

CRISPR/Cas9 in Planta Hairy Root Transformation: A Powerful Platform for Functional Analysis of Root Traits in Soybean

open access: yesPlants, 2022
Sequence and expression data obtained by next-generation sequencing (NGS)-based forward genetics methods often allow the identification of candidate causal genes. To provide true experimental evidence of a gene’s function, reverse genetics techniques are
Mohsen Niazian   +2 more
doaj   +1 more source

PheNominal: an EHR-integrated web application for structured deep phenotyping at the point of care

open access: yesBMC Medical Informatics and Decision Making, 2022
Background Clinical phenotype information greatly facilitates genetic diagnostic interpretations pipelines in disease. While post-hoc extraction using natural language processing on unstructured clinical notes continues to improve, there is a need to ...
James M. Havrilla   +8 more
doaj   +1 more source

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