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Genetics of Follicular Lymphoma Transformation
Cell Reports, 2014 Follicular lymphoma (FL) is an indolent disease, but 30%–40% of cases undergo histologic transformation to an aggressive malignancy, typically represented by diffuse large B cell lymphoma (DLBCL). The pathogenesis of this process remains largely unknown.
Laura Pasqualucci +18 more
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Plants, 2022 Sequence and expression data obtained by next-generation sequencing (NGS)-based forward genetics methods often allow the identification of candidate causal genes. To provide true experimental evidence of a gene’s function, reverse genetics techniques are
Mohsen Niazian +2 more
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Genetic Transformation in Citrus [PDF]
The Scientific World Journal, 2013 Citrus is one of the world’s important fruit crops. Recently, citrus molecular genetics and biotechnology work have been accelerated in the world. Genetic transformation, a biotechnological tool, allows the release of improved cultivars with desirable ...
Dicle Donmez +4 more
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Genotype-independent Agrobacterium rhizogenes-mediated root transformation of chickpea: a rapid and efficient method for reverse genetics studies [PDF]
Plant Methods, 2018 Chickpea (Cicer arietinum L.), an important legume crop is one of the major source of dietary protein. Developing an efficient and reproducible transformation method is imperative to expedite functional genomics studies in this crop.
Pooja Aggarwal +4 more
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Development of a rapid reverse genetics system for feline coronavirus based on TAR cloning in yeast
Frontiers in Microbiology, 2023 IntroductionReverse genetics has become an indispensable tool to gain insight into the pathogenesis of viruses and the development of vaccines. The yeast-based synthetic genomics platform has demonstrated the novel capabilities to genetically reconstruct
Hongmin Cao +3 more
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Establishment of a Genetic Transformation System in Guanophilic Fungus Amphichorda guana
Journal of Fungi, 2021 Fungi from unique environments exhibit special physiological characters and plenty of bioactive natural products. However, the recalcitrant genetics or poor transformation efficiencies prevent scientists from systematically studying molecular biological ...
Min Liang +5 more
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Genetics, Genomics, and Breeding in Melon
Agronomy, 2022 Melon is an important horticultural crop worldwide. The high diversity of melon makes it a model plant for various different properties. Some quantitative trait loci or candidates have been discovered, but few were verified as limiting genetic ...
Longlan Xu +4 more
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Frontiers in Plant Science, 2020 Setaria viridis (green foxtail) has been identified as a potential experimental model system to genetically and molecularly characterise the C4 monocotyledonous grasses due to its small physical size, short generation time and prolific seed production ...
Duc Quan Nguyen +4 more
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The transformation of medical genetics by clinical genomics: hubris meets humility [PDF]
Genetics in Medicine, 2019 Wayne W. Grody
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