Results 91 to 100 of about 569,350 (369)
Animal MicrobiomeFish health, growth and disease is intricately linked to its associated microbiome. Understanding the influence, source and ultimately managing the microbiome, particularly for vulnerable early life-stages, has been identified as one of the key ...
Jin Yan Lim +5 more
doaj +1 more source
mBio, 2018 Recent reports suggest that mosaic-like sequences within the mtr (multiple transferable resistance) efflux pump locus of Neisseria gonorrhoeae, likely originating from commensal Neisseria sp.
Corinne E. Rouquette-Loughlin +11 more
doaj +1 more source
Characterization of myeloproliferative neoplasms based on genetics only and prognostication of transformation to blast phase [PDF]
, 2023 Manja Meggendorfer +7 more
openalex +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
The genetic transformation of plastids
, 2007 Biolistic delivery of DNA initiated plastid transformation research and still is the most widelyused approach to generate transplastomic lines in both algae and higher plants. The principal designof transformation vectors is similar in both phylogenetic groups.
Hans-Ulrich Koop +3 more
openaire +2 more sources
Frontiers in ImmunologyIntroductionBrucellosis is a widespread zoonotic disease that poses a considerable challenge to global public health. Existing diagnostic methods for this condition, such as serological assays and bacterial culture, encounter difficulties due to their ...
Qi Wu +8 more
doaj +1 more source
Analytic approach to the evolutionary effects of genetic exchange [PDF]
, 2005 We present an approximate analytic study of our previously introduced model of evolution including the effects of genetic exchange. This model is motivated by the process of bacterial transformation. We solve for the velocity, the rate of increase of fitness, as a function of the fixed population size, $N$.
arxiv +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
Accurate estimation of homologue-specific DNA concentration-ratios in cancer samples allows long-range haplotyping [PDF]
, 2011 Interpretation of allelic copy measurements at polymorphic markers in cancer samples presents distinctive challenges and opportunities. Due to frequent gross chromosomal alterations occurring in cancer (aneuploidy), many genomic regions are present at ...
Gad Getz +2 more
core +1 more source
A one locus, biased mutation model and its equivalence to an unbiased model [PDF]
, 2004 Experimental data suggests that for some continuously varying characters under stabilising selection, mutation may cause a mean change in the value of the character. A one locus, mathematical model of a continuously varying biological character with this
Abramowitz +16 more
core +2 more sources