Results 111 to 120 of about 2,898,627 (344)

Natural variation of model mutant phenotypes in Ciona intestinalis [PDF]

open access: yes, 2008
The study of ascidians (Chordata, Tunicata) has made a considerable contribution to our understanding of the origin and evolution of basal chordates. To provide further information to support forward genetics in Ciona intestinalis, we used a combination ...
Annamaria Locascio   +68 more
core   +1 more source

Administering Blinatumomab via Continuous Intravenous Infusion in Pediatric Patients—A Single‐Institution Retrospective Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab, a CD19xCD3 bispecific T‐cell engager, has become standard therapy for children with de novo B‐cell acute lymphoblastic leukemia (B‐ALL). This retrospective review describes the experience of blinatumomab administration in pediatric patients.
Julia M. Hurley   +6 more
wiley   +1 more source

Molecular genetical analysis of the nitrate gene cluster of Aspergillus nidulans [PDF]

open access: yes, 2015
Putative DNA clones harbouring the nitrate gene cluster of Aspergillus nidulans was used in a number of transformation experiments to positively identify the clones.
Greaves, Philip Andrew
core  

Genetics [PDF]

open access: yes, 2009
Stimulated by a series of biotechnological developments, human geographers have begun a research engagement with genetic science. Through its transformation of the relationship between nature and society, genetics connects to the core disciplinary ...
E. Hall, Hall, E.; id_orcid
core   +1 more source

Improvement of Sickle Cell Disease Care Mitigates the Healthcare Utilization Induced by Increased Prevalence: Experience of a Tertiary Pediatric Center

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) has undergone major changes in the last decades. Its prevalence has been steadily increasing and numerous advances have been made in the management of the disease. However, the effect in real‐life setting of these major changes is unknown, particularly in a Canadian environment. Procedure We aimed to assess
Maude Cigna   +16 more
wiley   +1 more source

Genetic engineering of baker’s and wine yeasts using formaldehyde hyperresistance-mediating plasmids [PDF]

open access: yes, 2009
Yeast multi-copy vectors carrying the for maldehyde-resistance marker gene SFA have proved to be a valuable tool for research on industrially used strains of Saccharomyces cerevisiae.
Schmidt, Martin   +3 more
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Genetic transformation in melon [PDF]

open access: yes, 2012
10th EUCARPIA Meeting on Genetics and Breeding of Cucurbitaceae -- OCT 15-18, 2012 -- Antalya, TURKEYWOS: 000345687100079Melon is one of the species in Cucurbitaceae which has intense transformation researches for two decades.
Mendi, Y. Yalcin   +5 more
core  

Current Advancement and Future Prospects in Simplified Transformation-Based Plant Genome Editing [PDF]

open access: yes
Recent years have witnessed remarkable progress in plant biology, driven largely by the rapid evolution of CRISPR/Cas-based genome editing (GE) technologies.
Zhaolong Deng   +3 more
core   +1 more source

First Steps towards Underdominant Genetic Transformation of Insect Populations [PDF]

open access: yes, 2014
The idea of introducing genetic modifications into wild populations of insects to stop them from spreading diseases is more than 40 years old. Synthetic disease refractory genes have been successfully generated for mosquito vectors of dengue fever and ...
Reeves R. Guy   +24 more
core   +2 more sources

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