Results 141 to 150 of about 2,898,627 (344)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The development of a system to facilitate the stable expression of mammalian proteins in the filamentous fungus 'Aspergillus oryzae' [PDF]

open access: yes, 2012
Human interleukin 6 (hIL6) is a multifunctional cytokine effecting the function and proliferation of many cell types. The further understanding of hIL6 and its possible medical applications rely on the availability of this protein.
Macro, Janet Anne
core  

How genetics came to the unborn: 1960–2000 [PDF]

open access: yes, 2014
International audiencePrenatal diagnosis (PND) is frequently identified with genetic testing. The termination of pregnancy for foetal malformation was called ‘genetic abortion’, in spite of the fact that in many cases the malformation does not result ...
Löwy, Ilana
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Nuclear transformation and toolbox development [PDF]

open access: yes, 2017
Mussgnug JH. Nuclear transformation and toolbox development. In: Hippler M, ed. Chlamydomonas: Molecular Genetics and Physiology. Microbiology Monographs. Vol 30. 1st ed.
Hippler, Michael, Mussgnug, Jan H.
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Role of "Dehalococcoides" spp. in the anaerobic transformation of Hexachlorobenzene in European rivers [PDF]

open access: yes, 2011
The diffuse pollution by chlorinated organic compounds in river basins is a concern, due to their potential adverse effects on human health and the environment.
Tas, N.   +12 more
core   +1 more source

APPLYING TOGAF-BASED ENTERPRISE ARCHITECTURE IN THE HEALTHCARE SECTOR: A CASE STUDY OF THE NATIONAL CENTER FOR DIABETES IN JORDAN

open access: yesJordanian Journal of Computers and Information Technology
Technology implementation can significantly benefit organizations, but ensuring it aligns with their business needs and goals is crucial. Adopting an enterprise architecture approach can aid healthcare enterprises in overcoming challenges during the ...
Hania Al Omari   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Accelerating the translation and transformation of research knowledge in genetics to enhance innovation in Canada’s sheep industry [PDF]

open access: yes, 2018
2018 Small Ruminant Research ForumA discussion on how genomics can accelerate genetic improvement and the importance of translation and transformation of research knowledge in genetics to enhancing innovation in Canada's sheet ...
Canovas, Angela
core   +1 more source

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