Results 181 to 190 of about 462,471 (291)

MOKA: a pipeline for multiomics bridged SNP-set kernel association test. [PDF]

G3 (Bethesda)
Enoma D, Wang D, Kamdoum AGK, Polo RO, Long Q, He J.   +5 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

The nature of mutation: a legacy of bacterial genetics. [PDF]

Genetics
Lovett ST, Sass TH.
europepmc   +1 more source

Emerging strategies to target metastasis and therapy resistance in melanoma

Molecular Oncology, EarlyView.
Emerging studies propose new approaches to interfere with melanoma progression. In recognition of melanoma awareness month, at Molecular Oncology, we highlight recently published research articles, focusing on novel therapeutic targets driving metastatic spread and outlining different strategies to overcome resistance to BRAF inhibitors and anti‐PD‐1 ...
Amel Aziba
wiley   +1 more source

Genetic Manipulation in Sporothrix Species: Molecular Tools, Challenges, and Applications. [PDF]

J Fungi (Basel)
Barros M, Tavares M, Silvestre R, Peres da Silva R, Rodrigues F.   +4 more
europepmc   +1 more source

Interstitial stem cells in Hydra [PDF]

, 1987
Bosch, Thomas C. G., David, Charles N., Hobmayer, Engelbert, Holstein, Thomas W., Loomis, W. F., Schmidt, Tobias   +5 more
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

A toxin/antitoxin system targeting the replication sliding-clamp induces competence in Streptococcus pneumoniae. [PDF]

PLoS Genet
Maziero M, Juillot D, Mortier-Barrière I, Carballido-Lopez R, Campo N, Genevaux P, Bordes P, Polard P, Bergé M.   +8 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Stable transgene expression and CRISPR-mediated knock-in system of a bacteria-derived antibiotic selection gene in the green alga Ulva prolifera. [PDF]

BMC Plant Biol
Qin Z, Surnido W, Mizuta H, Uji T.
europepmc   +1 more source