Results 31 to 40 of about 2,864,901 (314)
Multiple testing correction in linear mixed models. [PDF]
, 2016 BackgroundMultiple hypothesis testing is a major issue in genome-wide association studies (GWAS), which often analyze millions of markers. The permutation test is considered to be the gold standard in multiple testing correction as it accurately takes ...
Eskin, Eleazar +3 more
core +2 more sources
Genetics of Transformed Follicular Lymphoma
Hemato, 2022 Histological transformation (HT) to a more aggressive disease–mostly diffuse large B-cell lymphoma–is considered one of the most dismal events in the clinical course of follicular lymphoma (FL).
Miguel Alcoceba +6 more
doaj +1 more source
An Evolutionary Reduction Principle for Mutation Rates at Multiple Loci [PDF]
, 2010 A model of mutation rate evolution for multiple loci under arbitrary selection is analyzed. Results are obtained using techniques from Karlin (1982) that overcome the weak selection constraints needed for tractability in prior studies of multilocus event
A. Eyre-Walker +60 more
core +2 more sources
Factors and Conditions That Impact Electroporation of
mSphere, 2020 An important risk factor for acquiring Clostridioides difficile infection is antibiotic use. Therefore, a detailed knowledge of the physiology and the virulence factors can help drive the development of new diagnostic tools and nonantibiotic therapeutic ...
Disha Bhattacharjee, Joseph A. Sorg
doaj +1 more source
Reproductive Biology and Endocrinology, 2022 Background There is a lack of biomarkers for distinguishing non-obstructive azoospermia (NOA) patients with successful sperm retrieval (Sp+) from those with failed sperm retrieval (Sp-).
Xiaoxiao Han +10 more
doaj +1 more source
The population genetics of urban and rural amphibians in North America
Molecular Ecology, 2021 Human land transformation is one of the leading causes of vertebrate population declines. These declines are thought to be partly due to decreased connectivity and habitat loss reducing animal population sizes in disturbed habitats.
C. Schmidt, C. Garroway
semanticscholar +1 more source
Efficient generation of recombinant influenza A viruses employing a new approach to overcome the genetic instability of HA segments. [PDF]
PLoS ONE, 2015 Influenza A viruses (IAVs) are the most relevant and continual source of severe infectious respiratory complications in humans and different animal species, especially poultry.
Ahmed Mostafa +5 more
doaj +1 more source
Genetic Transformation in Yeasts [PDF]
Journal of General Microbiology, 1974 SUMMARY: The transformability of 25 strains of yeasts belonging to 23 species in three genera - Saccharomyces, Hansenula and Candida - was investigated with respect to ten characters. Eighteen hour cultures at about the end of the log phase of growth, addition of 10 μg DNA/ml, and an incubation time of 30 min at 30 to 37 °C usually yielded best results.
N C, Khan, S P, Sen
openaire +2 more sources
Human Molecular Genetics, 2021 Methodological advances over the last three decades have led to a profound transformation in our understanding of the genetic origins of neuropsychiatric disorders. This is exemplified by the study of autism spectrum disorders (ASD) for which microarrays,
Katherine W. Eyring, D. Geschwind
semanticscholar +1 more source
Ornamental Plant Research, 2022 Leaf disc transformation is one of the traditional methods that are now widely used in chrysanthemum with highly economical and ornamental value in world flower production, but it depends on plant genotypes and is time consuming and complicated.
Sujuan Xu +6 more
doaj +1 more source