Results 101 to 110 of about 2,437,366 (312)

The Estonian organizations - the subjects of transformation [PDF]

, 2004
Estonia stayed fifty years under the communist regime. This paper explores the transformation of Estonian organizations within the framework of the Leavitt's model of change where the process is analyzed from the perspective of four organizational ...
Roots, H., Vadi, M.
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Designing knowledge-matching facilities for scaling climate-smart agriculture: A proposal for accelerating food systems’ transformation in a changing climate [PDF]

, 2020
The brief talks about designing knowledge-matching facilities for scaling climate-smart agriculture. This is a priority discussed in the International Workshop on Scaling up and out of Climate-smart Technologies and Practices for Sustainable Agriculture (
Dinesh, Dhanush, Koerner, Jana, Nagano, Akiko   +2 more
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Pancreatitis with use of new diabetic medications: a real-world data study using the post-marketing FDA adverse event reporting system (FAERS) database

Frontiers in Pharmacology
Background: Pancreatitis is characterized by inflammation of the pancreas and significantly affects quality of life. Less than 5% of pancreatitis cases are drug-induced, but recent evidence suggests a substantial risk associated with glucagon-like ...
Khalidah A. Alenzi, Khalidah A. Alenzi, Deemah Alsuhaibani, Bader Batarfi, Thamir M. Alshammari, Thamir M. Alshammari, Thamir M. Alshammari   +6 more
doaj   +1 more source

Comprehensive inventory of large hydropower systems in the Italian Alpine Region [PDF]

Earth System Science Data
Climate change raises the critical need to understand its impact on water resources, particularly as hydropower's role as a flexible, renewable energy source becomes more vital in planning for the energy system's decarbonization.
A. Galletti, A. Galletti, S. Zarghami Dastjerdi, S. Zarghami Dastjerdi, B. Majone   +4 more
doaj   +1 more source

Institutional transition and the problem of credible commitment [PDF]

, 2011
During the last phase of state socialism, the economic reforms attempted by these counties didn’t stop the collapse of communism. Neither did the free market economic reforms in the democratic West starting around 1975 bring progress and prosperity ...
Boettke, Peter
core  

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Examining the interaction between vertical and horizontal dimensions of state transformation

, 2009
Two dimensions of state transformation often analysed separately can be identified as vertical authority shifts between different levels of government and horizontal authority transfers between state and non-state domains.
Büchs, Milena
core   +1 more source