Results 61 to 70 of about 193,312 (244)
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
Transformation bending device emulated by graded-index waveguide
, 2012 We demonstrate that a transformation device can be emulated using a gradient-index waveguide. The effective index of the waveguide is spatially varied by tailoring a gradient thickness dielectric waveguide.
Akmansoy +32 more
core +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Anti-telephones in transformation optics: metamaterials with closed null geodesics
, 2015 We apply the methods of transformation optics to theoretical descriptions of spacetimes that support closed null geodesic curves. The metric used is based on frame dragging spacetimes, such as the van Stockum dust or the Kerr black hole.
Boston, S. Reece
core +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
, 2014 Based on the form-invariant of Maxwell's equations under coordinate transformations, we extend the theory of transformation optics to transformation magneto-statics, which can design magnets through coordinate transformations.
He, S., Sun, F.
core +2 more sources
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Non-paraxial design and fabrication of a compact OAM sorter in the telecom infrared
, 2019 A novel optical device is designed and fabricated in order to overcome the limits of the traditional sorter based on log-pol optical transformation for the demultiplexing of optical beams carrying orbital angular momentum (OAM).
Girardi, Marcello +5 more
core +1 more source
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
Design of a Low-Reflection Flat Lens Antenna Based on Conformal Transformation Optics. [PDF]
Micromachines (Basel), 2023 Nazarzadeh F, Heidari AA.
europepmc +1 more source