Results 61 to 70 of about 520,043 (268)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Dual-quaternion-based iterative algorithm of the three dimensional coordinate transformation

Earth, Planets and Space
Nowadays a unit quaternion is widely employed to represent the three-dimensional (3D) rotation matrix and then applied to the 3D similarity coordinate transformation.
Huaien Zeng, Zhihao Wang, Junfeng Li, Siyang Li, Junjie Wang, Xi Li   +5 more
doaj   +1 more source

Identification of Power Network Branch Parameters Based on State Space Transformation

IEEE Access, 2019
Deviations or errors in power system branch parameters will seriously affect the effectiveness of power system state estimation and subsequent advanced applications.
Haibo Zhang, Zhiwei Diao, Yunfeng Cui
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

The review and development of a modern GNSS network and datum in Uzbekistan

Geodesy and Geodynamics, 2017
This study is focused on the discussion of a modern GNSS network and datum in Uzbekistan. Considering the significance difference (up to 200 m) in positions of the local ellipsoidal datum and the global datum, the precise transformation parameters ...
Dilbarkhon Fazilova
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Quantitative Analysis of 4 × 4 Mueller Matrix Transformation Parameters for Biomedical Imaging

Photonics, 2019
Mueller matrix polarimetry is a potentially powerful technique for obtaining microstructural information of biomedical specimens. Thus, it has found increasing application in both backscattering imaging of bulk tissue samples and transmission microscopic
Wei Sheng, Weipeng Li, Ji Qi, Teng Liu, Honghui He, Yang Dong, Shaoxiong Liu, Jian Wu, Daniel S. Elson, Hui Ma   +9 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Improved Parameter Estimation of the Line-Based Transformation Model for Remote Sensing Image Registration

Journal of Imaging, 2017
The line-based transformation model (LBTM), built upon the use of affine transformation, was previously proposed for image registration and image rectification. The original LBTM first utilizes the control line features to estimate six rotation and scale
Ahmed Shaker, Said M. Easa, Wai Yeung Yan   +2 more
doaj   +1 more source