Results 71 to 80 of about 3,261,902 (400)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Leadership in Psychiatry – Enhancing Practice in the Indian Context

Journal of Psychiatry Spectrum
Leadership skills are essential in healthcare, especially in the field of psychiatry. India, being a middle-income nation, has seen major transformations both in the private and public health care sectors.
Pallavi Hoskote, Satish Ramaiah
doaj   +1 more source

KEMAMPUAN BERPIKIR ALJABAR SISWA SEKOLAH PENDIDIKAN DASAR KELAS V DAN KELAS VII: CROSS-SECTIONAL STUDY

Jurnal Pendidikan dan Kebudayaan, 2018
The study aimed to describe 1) students’ algebraic thinking ability of elementary school grade V, 2) students’ algebraic thinking ability of junior high school grade VII, and 3) the development of students’ algebraic thinking ability from ...
Dian Permatasari, Idris Harta
doaj   +1 more source

Follower‐rated leadership styles, leader behaviours, and leaders' thinking styles: A test of the cognitive experiential leadership model

Australian Journal of Psychology, 2020
Objective The Cognitive Experiential Leadership Model (CELM) predicts that leaders' thinking styles will be related to transformational leadership and effective leadership behaviours, especially influencing tactics and conflict handling styles.
Guy J. Curtis
doaj   +1 more source

$q$-Supercongruences from Jackson's $_8ϕ_7$ summation and Watson's $_8ϕ_7$ transformation [PDF]

, 2021
Chuanan Wei
openalex   +1 more source

Transforming vaccinology

Cell
The COVID-19 pandemic placed the field of vaccinology squarely at the center of global consciousness, emphasizing the vital role of vaccines as transformative public health tools. The impact of vaccines was recently acknowledged by the award of the 2023 Nobel Prize in Physiology or Medicine to Katalin Kariko and Drew Weissman for their seminal ...
Rino Rappuoli, Galit Alter, Bali Pulendran   +2 more
openaire   +3 more sources

Appell Transformation and Canonical Transforms [PDF]

Symmetry, Integrability and Geometry: Methods and Applications, 2011
The interpretation of the optical Appell transformation, as previously elaborated in relation to the free-space paraxial propagation under both a rectangular and a circular cylindrical symmetry, is reviewed. Then, the caloric Appell transformation, well known in the theory of heat equation, is shown to be amenable for a similar interpretation involving
openaire   +5 more sources

Perverse effects of other-referenced performance goals in an information exchange context [PDF]

A values-centered leadership model comprised of leader stakeholder and economic values, follower values congruence, and responsible leadership outcomes was tested using data from 122 organizational leaders and 458 of their direct reports.
Anseel, F., Janssen, O., Poortvliet, P.M., Yperen, N.W., van   +3 more
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Life cycle assessment of pharmaceutical tablet manufacturing: A comparative analysis and systems model integration framework

International Journal of Pharmaceutics: X
Pharmaceutical drug products in the form of tablets are produced via a series of manufacturing steps, transforming powder blends to compacted granules with carefully selected properties such as tensile strength and dissolution time.
Flora Bouchier, Astrid Boje, Gavin Reynolds   +2 more
doaj   +1 more source