Results 61 to 70 of about 80,747 (318)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Methodological approaches to the management of industrial enterprises

open access: yesПутеводитель предпринимателя, 2020
In the article the analysis of modern domestic management of the process of economic activities, methodological provisions allowing to develop nonlinear forms of cognition social and economic reality, to form a holistic, nature-oriented management ...
L. S. Mityuchenko, B. V. Kosolapov
doaj  

Parallel processes in clinical supervision: Implications for coaching mental health practitioners [PDF]

open access: yesInternational Journal of Evidence Based Coaching and Mentoring, 2011
This paper outlines the potential of parallel processes to enhance experiential learning opportunities in coaching for mental health practitioners. Traditional views of parallel processes in clinical supervision are examined in relation to how they can ...
Trevor P. Crowe   +4 more
doaj  

Capacity building through integration and transformational leadership - A case study

open access: yesHigher Learning Research Communications, 2011
This article suggests that educational managers can have an influence through leadership by establishing certain moderators that integrate and shape the faculty into a solid team working towards a high performing organisation.
Sacha Michael Stocklin
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Exploring the Transformational Potential of Adventure Tourism Experiences: Encounters and Connections with Nature [PDF]

open access: yes, 2021
Transformational tourism has been defined in a variety of ways, ranging from purposeful seeking of self-transformation (Ross, 2010), to incidental experiences of personal growth (Lean, 2012).
Pope, E.
core  

THE RELATIONSHIP BETWEEN MANAGERS' LEADERSHIP STYLES IN PHYSICAL EDUCATION OFFICES UNIVERSITIES AND SPORT VOLUNTEERS' SATISFACTION [PDF]

open access: yesPedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2012
The purpose of the present study was to investigate the relationship between managers' leadership styles in physical education offices universities and sport volunteers' satisfaction.
Reza Andam   +2 more
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

CLINICAL NURSES’ PERCEPTIONS TOWARD THEIR NURSE MANAGERS’ DEGREES OF TRANSFORMATIONAL LEADERSHIP AND TRUST [PDF]

open access: yes, 2017
Scholars have emphasized the importance of trust as a critical foundation of effective and successful leadership. However, empirical evidence on behaviors that promote trust in leadership remains scarce and lacking. It is postulated that transformational
Zahreddine, Hassan
core  

Leadership in Psychiatry – Enhancing Practice in the Indian Context

open access: yesJournal of Psychiatry Spectrum
Leadership skills are essential in healthcare, especially in the field of psychiatry. India, being a middle-income nation, has seen major transformations both in the private and public health care sectors.
Pallavi Hoskote, Satish Ramaiah
doaj   +1 more source

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