Results 81 to 90 of about 85,416 (307)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Integrating AI for In-Depth Segmentation of Coastal Environments in Remote Sensing Imagery

Remote Sensing
Mapping coastal landforms is critical for the sustainable management of ecosystems influenced by both natural dynamics and human activity. This study investigates the application of Transformer-based semantic segmentation models for pixel-level ...
Pelagia Drakopoulou, Paraskevi Tzouveli, Aikaterini Karditsa, Serafim Poulos   +3 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Effective Modeling of Leakage Inductance for use in Circuit Simulation

, 2008
Theoretical methods for the calculation of winding losses with respect to frequency have been well documented, but the variation in leakage inductance of magnetic components due to frequency has been less well addressed. In this paper Dowell’s well-known
Andrew D. Brown, Brown, Andrew, Peter R. Wilson, Wilson, Peter   +3 more
core   +1 more source

Compositionality of Model Transformations

Electronic Notes in Theoretical Computer Science, 2009
AbstractModel transformations can be used not only for code or platform-specific model generation, but also for denotational semantics definition, e.g. using process algebras as semantics for visual modeling languages.Denotational semantics of programming languages are by definition compositional.
Dénes Bisztray, Reiko Heckel, Hartmut Ehrig   +2 more
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Enhanced Multi-Task Traffic Forecasting in Beyond 5G Networks: Leveraging Transformer Technology and Multi-Source Data Fusion

Future Internet
Managing cellular networks in the Beyond 5G (B5G) era is a complex and challenging task requiring advanced deep learning approaches. Traditional models focusing on internet traffic (INT) analysis often fail to capture the rich temporal and spatial ...
Ibrahim Althamary, Rubbens Boisguene, Chih-Wei Huang   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Desempenho da proteção diferencial em transformadores de potência perante condições especiais de operação [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia ElétricaRelés digitais vêm gradualmente substituindo os relés eletromecânicos porque são mais sensíveis, mais flexíveis e várias ...
Verney, Luiz Henrique Costa de
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source