Results 81 to 90 of about 2,301,421 (250)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Enhancing the Sensitivity of Power Transformer Differential Protection in Power Systems.

Zanco Journal of Pure and Applied Sciences
Differential protection is a fundamental protection scheme used to detect and isolate internal faults in power transformers. It works on the principle of comparing the currents entering and leaving the protected zone (transformer).
Aso Farooq Hayder, Ismael Kareem Saeed
doaj   +1 more source

Transformer protection, automation and monitoring systems [PDF]

E3S Web of Conferences
This paper presents the results of research on improving the protection, automation and monitoring systems of power transformers (PT) in 6-35 kV distribution networks.
Piskunov Sergey, Mokeev Alexey, Ulyanov Dmitry   +2 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Dependability Analysis of the Negative-Sequence Turn-to-Turn Fault Protection Schemes for MMC-HVDC Converter Transformers

International Journal of Electrical Power & Energy Systems
This paper addresses two complex areas of research: the detection of turn-to-turn faults (TTF) in power transformers and the impact of inverter-based resources on the TTF protection scheme operation. Detecting turn-to-turn faults in power transformers by
Frank Mieske, Krzysztof Solak, Waldemar Rebizant   +2 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Design the protection of a 35/0.4 kv, 400 kva transformer and low voltage gird

, 2018
The home electrical system began to see larger circuits which required more protection which was provided by fuses. These fuses have been used as the main electrical service protection being enclosed in a pull-out assembly that also served as a service ...
Alkhater, mahmoud
core  

Reliability Improvement Strategy for Transformer Zero-Sequence Differential Protection Based on Zero-Sequence Current Amplitude Difference Characteristics

Zhongguo dianli
The zero-sequence differential protection of transformer may cause the reliability to decrease or even malfunction due to the fault of current transformer (CT) when dealing with complex inrush current and fault.
Junchao ZHENG, Yaming GE, Xiangping KONG, Xuchao REN, Shi CHEN, Chenqing WANG   +5 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Simulation of dielectric frequency response of transformer insulation system

, 2013
Frequency domain spectroscopy has been widely used to monitor the condition of insulation system in power transformers. For a core type of transformer, a simplified XY model of a duct has been developed which allows one to examine the contribution from ...
Yu, Guo, Chen, George
core   +1 more source