Results 61 to 70 of about 9,150 (262)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

A Survey on Fault Clearing and Protection Technology of Power Electronic Transformer in Distribution Network

Kongzhi Yu Xinxi Jishu, 2017
Protection system for power electronic transformer is an important measure to ensure its safe and stable operation in engineering application. Firstly, taking AC-DC-AC type power electronic transformer as an example, this paper pointed out its topology ...
ZHOU Tingdong, XU Yonghai
doaj  

Enhancing the Sensitivity of Power Transformer Differential Protection in Power Systems.

Zanco Journal of Pure and Applied Sciences
Differential protection is a fundamental protection scheme used to detect and isolate internal faults in power transformers. It works on the principle of comparing the currents entering and leaving the protected zone (transformer).
Aso Farooq Hayder, Ismael Kareem Saeed
doaj   +1 more source

Transformer protection, automation and monitoring systems [PDF]

E3S Web of Conferences
This paper presents the results of research on improving the protection, automation and monitoring systems of power transformers (PT) in 6-35 kV distribution networks.
Piskunov Sergey, Mokeev Alexey, Ulyanov Dmitry   +2 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Dependability Analysis of the Negative-Sequence Turn-to-Turn Fault Protection Schemes for MMC-HVDC Converter Transformers

International Journal of Electrical Power & Energy Systems
This paper addresses two complex areas of research: the detection of turn-to-turn faults (TTF) in power transformers and the impact of inverter-based resources on the TTF protection scheme operation. Detecting turn-to-turn faults in power transformers by
Frank Mieske, Krzysztof Solak, Waldemar Rebizant   +2 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Reliability Improvement Strategy for Transformer Zero-Sequence Differential Protection Based on Zero-Sequence Current Amplitude Difference Characteristics

Zhongguo dianli
The zero-sequence differential protection of transformer may cause the reliability to decrease or even malfunction due to the fault of current transformer (CT) when dealing with complex inrush current and fault.
Junchao ZHENG, Yaming GE, Xiangping KONG, Xuchao REN, Shi CHEN, Chenqing WANG   +5 more
doaj   +1 more source