Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Simulation of checking of mechanical state of the transformer windings by nanosecond impulse.
The detailed electrical model of the transformer windings was developed. The possibility of detecting negligible changes in the geometrical pattern of the windings was investigated by testing of the impulses with nanosecond rising edge.
Semenov A.S. +3 more
doaj +1 more source
Winding-to-ground fault location in power transformer windings using combination of discrete wavelet transform and back-propagation neural network. [PDF]
Chiradeja P, Ngaopitakkul A.
europepmc +1 more source
Pembangunan dan penilaian sistem 'template' soal selidik berasaskan web (e-templete questionnaire) [PDF]
Kajian ini dijaiankan bagi meninjau keboiehgunaan dan tahap mesra pengguna terhadap g-?e?77p/a/g soal selidik. Fokus utama kajian ini adaiah (i) menilai tahap keboiehgunaan
Abu Bakar, Muhammad Helmi
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Active noise compensation for multichannel magnetocardiography in an unshielded environment [PDF]
A multichannel high-T/sub c/-SQUID-based heart scanner for unshielded environments is under development, Outside a magnetically shielded room, sensitive SQUID measurements are possible using gradiometers.
Aarnink, W.A.M. +6 more
core +3 more sources
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Digital control of dual-load LCLC resonant converters [PDF]
The paper proposes the analysis, design and realisation of dual-output resonant LCLC converters with independent output regulation, employing a single power stage and combined PWM and frequency control.
Ang, Y A +3 more
core +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Diagnosis of axial displacement in transformer windings using finite element analysis
Transformer is one of the main equipment in the power system and power quality of the power system mainly depends on the working of the power transformer. Leakage reactance is one of the main parameters of the transformer.
Kamran Dawood +2 more
doaj +1 more source

