Results 81 to 90 of about 247,556 (284)

Numerical and analytical investigations of the water immersion cooling strategy for a permanent magnet synchronous motor

open access: yesIET Electric Power Applications
Permanent magnet synchronous motors (PMSMs) experience considerable performance degradation due to the rise in temperature and the resulting partial demagnetisation in the PMs, as well as the shortenings in the insulations' lifetime.
Tohid Sharifi
doaj   +1 more source

Efficient deep learning algorithms for lower grade gliomas cancer MRI image segmentation: A case study [PDF]

open access: yesAUT Journal of Mathematics and Computing
This study explores the use of efficient deep learning algorithms for segmenting lower grade gliomas (LGG) in medical images. It evaluates various pre-trained atrous-convolutional architectures and U-Nets, proposing a novel transformer-based approach ...
AmirReza BabaAhmadi, Zahra FallahPour
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

On a New Notion of Partial Refinement

open access: yes, 2013
Formal specification techniques allow expressing idealized specifications, which abstract from restrictions that may arise in implementations. However, partial implementations are universal in software development due to practical limitations.
Sekerinski, Emil, Zhang, Tian
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Stray Losses in Structural Components of Power Transformers

open access: yesEnergies
The paper provides a comprehensive overview of stray losses in conductive structural parts of power transformers, addressing the effects of stray magnetic fields on simple conductive plates, the distribution of additional losses across structural ...
Stipe Mikulić, Damir Žarko
doaj   +1 more source

Design of microstrip components by computer [PDF]

open access: yes, 1972
Development of computer programs for component analysis and design aids used in production of microstrip components is discussed. System includes designs for couplers, filters, circulators, transformers, power splitters, diode switches, and ...
Cisco, T. C.
core   +2 more sources

A Recipe for State-and-Effect Triangles

open access: yes, 2017
In the semantics of programming languages one can view programs as state transformers, or as predicate transformers. Recently the author has introduced state-and-effect triangles which capture this situation categorically, involving an adjunction between
Jacobs, Bart
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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