Results 131 to 140 of about 233,638 (252)

Latent-Transforming growth factor - β Binding protein 1 (LTBP1) in corneal stroma. [PDF]

Matrix Biol Plus
Poonen-Honig I, Acosta AC, Sun M, Emerick V, Avila MY, Margo CE, Espana EM.   +6 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Transforming growth factor β induced as a novel secreted immune checkpoint counterinhibiting human tumor-associated T cells. [PDF]

J Immunother Cancer
Rosado MM, Timperi E, Melaiu O, Vitale S, Bachy S, Grimaldi A, Corrado M, Mancini V, Leonti G, Conti F, Cammarata I, Celardo I, Kucykowicz S, Aidoo-Micah G, Gragera P, Accapezzato D, Del Ben M, D'Oria V, De Stefanis C, Forcina L, Frattaroli F, Picchetto A, Chiaretti M, D'Ambrosio G, Giannini G, Belardinilli F, Scarinci A, Grazi GL, Musarò A, Maini MK, Fiori ME, Fruci D, Hennino A, Barnaba V.   +33 more
europepmc   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source

Transforming Growth Factor-β Signaling in Alcohol-Associated Liver Disease: A Multicellular Perspective. [PDF]

Am J Pathol
Zou H, Wang S, Huang C, Dooley S, Meindl-Beinker NM.   +4 more
europepmc   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons, Nuria Guillen, Jordi Sarto, Neus Falgàs, Sergi Borrego‐Écija, Diana Esteller‐Gauxax, Magda Castellví, Adrià Tort‐Merino, Agnès Pérez‐Millan, Anna Antonell, Josep M. Augè Fradera, Gerard Piñol, Iolanda Riba, Anna Carnes‐Vendrell, Marta Cullell, Maria Teresa Osuna, Lorena Bajo, Teresa Romero, Eva Bonjoch, Joan Bello, Susana Fernández, Marta Balagué, Isabel Gómez‐Ruiz, Anuncia Boltes, Claustre Pont, Raquel Cuevas, Sara Carrillo, Laura Iglesias, Teresa Maria Casadevall Codina, Lorena Grau Guinea, Fernando Jose Espada, Raquel Sánchez‐Valle, Mircea Balasa, Albert Lladó   +33 more
wiley   +1 more source

Pirfenidone Mitigates Transforming Growth Factor-β-induced Inflammation after Viral Infection. [PDF]

Am J Respir Cell Mol Biol
Thomas BJ, Kan-O K, Gantier MP, Simpson I, Chitty JG, Lam M, Dousha L, Gottschalk TA, Lawlor KE, Tate MD, Ruwanpura S, Seow HJ, Loveland KL, Deshpande S, Li X, Hamza K, King PT, Elias JA, Vlahos R, Bourke JE, Bardin PG.   +20 more
europepmc   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

The Transforming Growth Factor β Genes and Susceptibility to Musculoskeletal Injuries in a Physically Active Caucasian Cohort. [PDF]

J Clin Med
Rzeszutko-Bełzowska A, Leońska-Duniec A.   +1 more
europepmc   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source