Myofibroblasts and Transforming Growth Factor-Beta1 in Reactive Gingival Overgrowths [PDF]
Objectives: The aim of this study was to detect the presence of myofibroblasts and transforming growth factor-beta1 in fibrous and ossifying-fibrous epulis and their possible contribution to the collagenous connective tissue formation.
Apostolos Epivatianos +2 more
doaj +7 more sources
Transforming Growth Factor-Beta1 in Diabetic Kidney Disease [PDF]
Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease (ESRD) worldwide. Renin-angiotensin-aldosterone system (RAAS) inhibitors and sodium-glucose co-transporter 2 (SGLT2) inhibitors have shown efficacy in reducing the risk of ESRD.
Lijun Zhao, Yutong Zou, Fang Liu
doaj +5 more sources
Transforming Growth Factor-Beta1 and Human Gingival Fibroblast-to-Myofibroblast Differentiation: Molecular and Morphological Modifications [PDF]
After oral mucosal injury, the healing response following specific steps that lead to wound closure and to tissue repair. Multiple cell populations are involved in this process; in particular, fibroblasts play a key role in the production of ...
Guya D. Marconi +9 more
doaj +2 more sources
Binding Behavior between Transforming-Growth-Factor-Beta1 and Its Receptor Reconstituted in Biomimetic Membranes [PDF]
Transforming growth factor β1 (TGF-β1) is critical to cell differentiation, proliferation, and apoptosis. It is important to understand the binding affinity between TGF-β1 and its receptors. In this study, their binding force was measured using an atomic
Gounhanul Shin +3 more
doaj +2 more sources
Transforming growth factor beta1 targets estrogen receptor signaling in bronchial epithelial cells [PDF]
Background Sex differences in idiopathic pulmonary fibrosis (IPF) suggest a protective role for estrogen (E2); however, mechanistic studies in animal models have produced mixed results.
L. Cody Smith +6 more
doaj +2 more sources
Anti-fibrotic Actions of Equine Interleukin-10 on Transforming Growth Factor-Beta1-Stimulated Dermal Fibroblasts Isolated From Limbs of Horses [PDF]
Fibroproliferative disorders occur in both humans and horses following skin injury. In horses, wound healing on the limb is often complicated by the formation of fibroproliferative exuberant granulation tissue, characterized by persistent expression of ...
Lyn M. Wise +5 more
doaj +2 more sources
Post-transcriptional regulation of Transforming Growth Factor Beta-1 by microRNA-744. [PDF]
Transforming Growth Factor Beta-1 (TGF-β1) is a pleiotropic cytokine that is of central importance in wound healing, inflammation, and in key pathological processes including cancer and progressive tissue fibrosis.
John Martin +6 more
doaj +1 more source
Purpose Herein we evaluated the effects of platelet concentrate (PC) and platelet-poor plasma (PPP) on bone repair using noncritical defects in the calvaria of rabbits and compared them to the presence of TGF-β1 and osteocalcin on reparative sites ...
Marco Antonio de Oliveira-Filho +8 more
doaj +1 more source
Objective: To evaluate the effect of resveratrol against CCl4- induced nephrotoxicity. Methods: Forty-two male Wistar rats were divided into seven groups randomly.
Saeed Mohammadi +5 more
doaj +1 more source
TGF-β1 on induced osteogenic differentiation of human dermal fibroblast [PDF]
PURPOSE: To evaluate the role of transforming growth factor beta 1 (TGF-β1) on the induced osteogenic differentiation of human dermal fibroblasts. METHODS: We performed four groups with cultured dermal fibroblasts according to the culture medium: CONTROL
Antonio Carlos Aloise +4 more
doaj +1 more source

