Results 41 to 50 of about 41,942 (251)

Resveratrol downregulates TGF-β1 and Smad3 expression and attenuates oxidative stress in CCl4-induced kidney damage in rats

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2020
Objective: To evaluate the effect of resveratrol against CCl4- induced nephrotoxicity. Methods: Forty-two male Wistar rats were divided into seven groups randomly.
Saeed Mohammadi   +5 more
doaj   +1 more source

Transforming growth factor beta1 (TGF-ß1) levels in a rat model of induced pleural empyema [PDF]

open access: yesActa Cirúrgica Brasileira, 2018
Purpose: To evaluate the concentration of transforming growth factor beta 1 (TGFB1) levels in a rat pleural effusion obtained by inoculation of intrapleural bacteria or turpentine through thoracentesis.
Samanta Sarmento da Silva   +7 more
doaj   +1 more source

Transforming Growth Factor-β1 to the Bone [PDF]

open access: yesEndocrine Reviews, 2005
TGF-β1 is a ubiquitous growth factor that is implicated in the control of proliferation, migration, differentiation, and survival of many different cell types. It influences such diverse processes as embryogenesis, angiogenesis, inflammation, and wound healing. In skeletal tissue, TGF-β1 plays a major role in development and maintenance, affecting both
Katrien, Janssens   +3 more
openaire   +2 more sources

Role of TGF-beta1 and MAP kinases in the antiproliferative effect of aspirin in human vascular smooth muscle cells. [PDF]

open access: yesPLoS ONE, 2010
We aimed to test the antiproliferative effect of acetylsalicylic acid (ASA) on vascular smooth muscle cells (VSMC) from bypass surgery patients and the role of transforming growth factor beta 1 (TGF-beta1).VSMC were isolated from remaining internal ...
Santiago Redondo   +8 more
doaj   +1 more source

Differential Expression of miR-21-5p, miR-20a-5p, TGF-β1, and TGF-β Receptor 2 in Skin, Serum, and Lung Samples Exposed to Sulfur Mustard

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2023
Sulfur mustard (SM) or mustard gas is a blister chemical agent that causes pulmonary damage by triggering inflammation and oxidative injury. Alterations in microRNA (miR) transcript levels are found in pulmonary diseases and even inflammation. Therefore,
Mohadeseh Valizadeh   +3 more
doaj   +1 more source

Suppressive effects of transforming growth factor-beta1 produced by hepatocellular carcinoma cell lines on interferon-gamma production by peripheral blood mononuclear cells. [PDF]

open access: yes, 2002
Transforming growth factor-beta1 (TGF-beta1) exerts potent immunosuppressive effects. In this study, we investigated the potential role of TGF-beta1 produced by hepatocellular carcinoma (HCC) cell lines in immunosuppression mechanisms.
Fujiwara, Akiko   +9 more
core   +1 more source

Transforming growth factor beta-1 and vascular endothelial growth factor in the recovery and formation of skin scars

open access: yesRUDN Journal of Medicine, 2021
Relevance. Scars are multi-tissue structures that significantly reduce the quality of life of the young, able-bodied population. The most socially significant variants are represented by hypertrophic and keloid postoperative scars and scars after burns ...
Varvara G. Nikonorova   +2 more
doaj   +1 more source

Enhanced serum concentrations of transforming growth factor-beta1 in simple fatty liver: is it really benign?

open access: yesJournal of Translational Medicine, 2008
Background Inside the spectrum of non-alcoholic fatty liver disease, simple fatty liver is generally thought of as being "non progressive", differently from non-alcoholic steatohepatitis, which increases in severity due to the presence of apoptosis ...
Contaldo Franco   +9 more
doaj   +1 more source

Testicular expression of the TGF-B1 system and the control of Leydig cell proliferation [PDF]

open access: yes, 2013
Transforming growth factor beta 1 (TGF-beta1) is a key regulator that modulates male reproductive function. Testicular TGF-beta1 modulates the steroidogenesis of Leydig cells, the organization of peritubular myoid cells, testis development and ...
Calandra, Ricardo Saul   +2 more
core   +2 more sources

TGF-beta 1-induced epithelial-to-mesenchymal transition and therapeutic intervention in diabetic nephropathy [PDF]

open access: yes, 2010
Background/Aims: Epithelial-to-mesenchymal cell transformation (EMT) is the trans-differentiation of tubular epithelial cells into myofibroblasts, an event underlying progressive chronic kidney disease in diabetes, resulting in fibrosis.
Hills, Claire E., Squires, Paul E.
core   +1 more source

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