Results 31 to 40 of about 9,295,419 (200)
Genetic control of the circulating concentration of transforming growth factor type beta1 [PDF]
Human Molecular Genetics, 1999 The concentration of transforming growth factor beta (TGF-beta) in plasma has been correlated with the development of several diseases, including atherosclerosis and certain forms of cancer. However, the mechanisms that control the concentration of TGF-beta in plasma are poorly understood. In a study of 170 pairs of female twins (average age 57.7 years)
D J, Grainger +7 more
openaire +2 more sources
Shen-Kang protects against tacrolimus-induced renal injury [PDF]
The Korean Journal of Internal Medicine, 2019 Background/Aims Evidence suggests that Shen-Kang (SK), a traditional Chinese herbal medicine, protects against various types of renal injury. In this study, we evaluated whether SK treatment confers renoprotection in a rat model of chronic tacrolimus ...
Long Ye Zhang +9 more
doaj +1 more source
Smad4 and ERK2 stimulated by transforming growth factor beta1 in rhabdomyosarcoma
Chinese Medical Journal, 2007 Transforming growth factor beta (TGF-beta) plays an essential role in the regulation of normal physiologic processes of cells. TGF-beta has been shown to regulate several mitogen-activated protein kinases (MAPK) pathways in several epithelial cells. However, the effects of TGF-beta on soft tissue sarcoma are seldom reported.
Hua, Guo +5 more
openaire +2 more sources
, 2001 Transforming growth factor beta1 treatment of keratinocytes results in a suppression of differentiation, an induction of extracellular matrix production, and a suppression of growth.
Cavanagh, Lois L. +2 more
core +1 more source
Brazilian Oral Research: Bioactive molecules stored in dentin, such as transforming growth factor beta1 (TGF-b1), may be involved in the signaling events related to dental tissue repair.
Lidiany Freitas GONÇALVES +7 more
doaj +1 more source
, 2007 Recent studies have shown that myostatin, first identified as a negative regulator of skeletal muscle growth, may also be involved in the formation of fibrosis within skeletal muscle.
Huard, Johnny +8 more
core +1 more source
Neurobiology of Pain, 2022 Low-dose interleukin-2 (LD-IL-2) treatment has been shown to effectively reverse chronic migraine-related behaviors and the sensitization of trigeminal ganglion (TG) neurons through expansion and activation of peripheral regulatory T cells (Tregs) in ...
Zhaohua Guo +5 more
doaj +1 more source
Irisin Regulates the Functions of Hepatic Stellate Cells [PDF]
Endocrinology and Metabolism, 2020 Background Hepatic stellate cells (HSCs) are known to play a fundamental role in the progression of liver fibrosis. Once HSCs are activated, they are involved in proliferation, migration, and contractility which are characteristics of liver fibrogenesis.
Hanh Nguyen Dong +4 more
doaj +1 more source
, 2007 Langerhans cells (LC) represent the cutaneous contingent of dendritic cells (DC). Their development critically depends on transforming growth factor beta1 (TGF-beta1) as demonstrated by analysis of TGF-beta1(-/-) mice, which lack LC.
Bartz, C. +29 more
core +1 more source
Transforming Growth Factor-β1 Is a Negative Modulator of Adult Neurogenesis [PDF]
Journal of Neuropathology and Experimental Neurology, 2006 Transforming growth factor (TGF)-beta1 has multiple functions in the adult central nervous system (CNS). It modulates inflammatory responses in the CNS and controls proliferation of microglia and astrocytes. In the diseased brain, TGF-beta1 expression is upregulated and, depending on the cellular context, its activity can be beneficial or detrimental ...
Frank-Peter, Wachs +7 more
openaire +2 more sources