Transforming Growth Factor-Beta1 in Diabetic Kidney Disease [PDF]
Frontiers in Cell and Developmental Biology, 2020 Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease (ESRD) worldwide. Renin-angiotensin-aldosterone system (RAAS) inhibitors and sodium-glucose co-transporter 2 (SGLT2) inhibitors have shown efficacy in reducing the risk of ESRD.
Lijun Zhao, Yutong Zou, Fang Liu
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Binding Behavior between Transforming-Growth-Factor-Beta1 and Its Receptor Reconstituted in Biomimetic Membranes [PDF]
Membranes, 2023 Transforming growth factor β1 (TGF-β1) is critical to cell differentiation, proliferation, and apoptosis. It is important to understand the binding affinity between TGF-β1 and its receptors. In this study, their binding force was measured using an atomic
Gounhanul Shin +3 more
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Myofibroblasts and Transforming Growth Factor-Beta1 in Reactive Gingival Overgrowths [PDF]
eJournal of Oral Maxillofacial Research, 2013 Objectives: The aim of this study was to detect the presence of myofibroblasts and transforming growth factor-beta1 in fibrous and ossifying-fibrous epulis and their possible contribution to the collagenous connective tissue formation.
Apostolos Epivatianos +2 more
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Transforming Growth Factor-Beta1 and Human Gingival Fibroblast-to-Myofibroblast Differentiation: Molecular and Morphological Modifications [PDF]
Frontiers in Physiology, 2021 After oral mucosal injury, the healing response following specific steps that lead to wound closure and to tissue repair. Multiple cell populations are involved in this process; in particular, fibroblasts play a key role in the production of ...
Guya D. Marconi +9 more
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Transforming growth factor beta1 targets estrogen receptor signaling in bronchial epithelial cells [PDF]
Respiratory Research, 2018 Background Sex differences in idiopathic pulmonary fibrosis (IPF) suggest a protective role for estrogen (E2); however, mechanistic studies in animal models have produced mixed results.
L. Cody Smith +6 more
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Induction of gastric cancer cell adhesion through transforming growth factor-beta1-mediated peritoneal fibrosis [PDF]
Journal of Experimental & Clinical Cancer Research, 2010 Background Peritoneal dissemination is one of the main causes of death in gastric cancer patients. Transforming growth factor-beta1 (TGF-β1), one of the most potent fibrotic stimuli for mesothelial cells, may play a key role in this processing.
Ma Xiao-Yang +8 more
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Anti-fibrotic Actions of Equine Interleukin-10 on Transforming Growth Factor-Beta1-Stimulated Dermal Fibroblasts Isolated From Limbs of Horses [PDF]
Frontiers in Veterinary Science, 2020 Fibroproliferative disorders occur in both humans and horses following skin injury. In horses, wound healing on the limb is often complicated by the formation of fibroproliferative exuberant granulation tissue, characterized by persistent expression of ...
Lyn M. Wise +5 more
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Indian Journal of Pathology and Microbiology, 2014 Background: Insulin-like growth factor (IGF), transforming growth factor-beta1 (TGF-β1), and vascular endothelial growth factor (VEGF) are commonly studied growth factors, but little data are available on the immunohistochemical expression of these ...
Hamide Sayar +5 more
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Latent Transforming Growth Factor-beta1 Functionalised Electrospun Scaffolds Promote Human Cartilage Differentiation: Towards an Engineered Cartilage Construct [PDF]
Archives of Plastic Surgery, 2013 Background To overcome the potential drawbacks of a short half-life and dose-related adverse effects of using active transforming growth factor-beta 1 for cartilage engineering, a cell-mediated latent growth factor activation strategy was developed ...
Erh-Hsuin Lim +3 more
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Growth regulation of simian and human AIDS-related non-Hodgkin's lymphoma cell lines by TGF-β1 and IL-6 [PDF]
BMC Cancer, 2007 Background AIDS-related non-Hodgkin's lymphoma (AIDS-NHL) is the second most frequent cancer associated with AIDS, and is a frequent cause of death in HIV-infected individuals. Experimental analysis of AIDS-NHL has been facilitated by the availability of
Levy Laura S +2 more
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