Results 21 to 30 of about 9,295,419 (200)

Transforming growth factor beta-1 and vascular endothelial growth factor in the recovery and formation of skin scars

RUDN Journal of Medicine, 2021
Relevance. Scars are multi-tissue structures that significantly reduce the quality of life of the young, able-bodied population. The most socially significant variants are represented by hypertrophic and keloid postoperative scars and scars after burns ...
Varvara G. Nikonorova, Vladimir V. Chrishtop, Tatyana A. Rumyantseva   +2 more
doaj   +1 more source

Transforming growth factor-beta1 and glial growth factor 2 reduce neurotrophin-3 mRNA expression in cultured Schwann cells via a cAMP-dependent pathway.

, 1999
The aim of the study was to determine which factors regulated the expression of neurotrophin-3 (NT-3) mRNA in cultured primary Schwann cells derived from sciatic nerve of neonatal rats.
Campana, W, Tomlinson, D, Fernyhough, P., Cai, F   +3 more
core   +7 more sources

Enhanced serum concentrations of transforming growth factor-beta1 in simple fatty liver: is it really benign?

Journal of Translational Medicine, 2008
Background Inside the spectrum of non-alcoholic fatty liver disease, simple fatty liver is generally thought of as being "non progressive", differently from non-alcoholic steatohepatitis, which increases in severity due to the presence of apoptosis ...
Contaldo Franco, Pasanisi Fabrizio, Chianese Domenico, Di Minno Matteo N, Tarantino Marianna, Riccio Antonio, Conca Paolo, Tarantino Giovanni, Scopacasa Francesco, Capone Domenico   +9 more
doaj   +1 more source

Transforming growth factor beta-1 (TGF-β1) expression in patients with adenomyosis [PDF]

Revista Brasileira de Ginecologia e Obstetrícia
Objective: To compare Transforming growth factor beta-1 (TGF-β1) expression in patients with and without adenomyosis. Methods: A prospective design was performed including 49 patients submitted to hysterectomy.
Andreia Jacobo, Renata Fogaça Borges, Carlos Augusto Bastos de Souza, Vanessa Krebs Genro, João Sabino Cunha-Filho   +4 more
doaj   +1 more source

Transforming growth factor-β1 and TGF-β2 act synergistically in the fibrotic pathway in oral submucous fibrosis: An immunohistochemical observation

Indian Journal of Medical and Paediatric Oncology, 2015
Background and objectives: Oral Submucous Fibrosis (OSF) is a potentially malignant oral disorder which leads to fibrosis of the oral mucosa and has a high rate of malignant transformation.
Venkatesh Viswanath Kamath, Shruti Krishnamurthy, Krishnanand P Satelur, Komali Rajkumar   +3 more
doaj   +1 more source

The recombinant proregion of transforming growth factor beta1 (latency-associated peptide) inhibits active transforming growth factor beta1 in transgenic mice. [PDF]

Proceedings of the National Academy of Sciences, 1996
All three isoforms of transforming growth factors beta (TGF-betal, TGF-beta2, and TGF-beta3) are secreted as latent complexes and activated extracellularly, leading to the release of the mature cytokines from their noncovalently associated proregions, also known as latency-associated peptides (LAPs).
E P, Böttinger, V M, Factor, M L, Tsang, J A, Weatherbee, J B, Kopp, S W, Qian, L M, Wakefield, A B, Roberts, S S, Thorgeirsson, M B, Sporn   +9 more
openaire   +2 more sources

Serum level of transforming growth factor-beta1 in major idiopathic interstitial pneumonia

The Egyptian Journal of Bronchology, 2020
Background Different inflammatory cytokines play a role in the mechanism and pathogenesis of fibrosis in idiopathic interstitial pneumonia (IIP). Transforming growth factor-beta1 (TGF-β1) has become a subject of interest.
Mohamed W. Zakaria, Reem I. El-Korashy, Samah Selim, Ingy Badawy, Kwashi J. Amum   +4 more
doaj   +1 more source

Activation of transforming growth factor beta by malaria parasite-derived metalloproteinases and a thrombospondin-like molecule [PDF]

, 2003
Much of the pathology of malaria is mediated by inflammatory cytokines (such as interleukin 12, interferon gamma, and tumor necrosis factor alpha), which are part of the immune response that kills the parasite.
Riley, Eleanor M, Sultan, Ali A, J. Brian de Souza, de Souza, J Brian, Eleanor M. Riley, Corran, Patrick H, Patrick H. Corran, Omer, Fakhreldin M, Riley, EM, Sultan, AA, Corran, PH, Ali A. Sultan, Omer, FM, de Souza, JB, Fakhreldin M. Omer   +14 more
core   +1 more source

Association between Genetic Variants of Transforming Growth Factor-β1 and Susceptibility of Pneumoconiosis: A Meta-analysis

Chinese Medical Journal, 2017
Background: Transforming growth factor-beta 1 (TGF-β1) and gene variants have been extensively studied in various human diseases. For example, TGF-β1 polymorphisms were associated with fibrosis and pneumoconiosis, but the data remained controversial. The
Chang-Wen Deng, Xing-Xing Zhang, Jin-Huan Lin, Li-Fei Huang, Yu-Lan Qu, Chong Bai   +5 more
doaj   +1 more source

Differences in Hypertrophic Scar Fibroblasts according to Scar Severity: Expression of Transforming Growth Factor beta1 at the mRNA and Protein Levels [PDF]

Archives of Aesthetic Plastic Surgery, 2015
Background Hypertrophic scars result from excessive collagen deposition and increased transforming growth factor beta-1 (TGF-beta1) levels. We hypothesized that the expression of TGF-beta1 mRNA and protein would increase with the clinical severity of ...
Se Young Kim, Seung Min Nam, Eun Soo Park, Yong Bae Kim   +3 more
doaj   +1 more source