Results 21 to 30 of about 13,909 (174)

Enhanced serum concentrations of transforming growth factor-beta1 in simple fatty liver: is it really benign?

Journal of Translational Medicine, 2008
Background Inside the spectrum of non-alcoholic fatty liver disease, simple fatty liver is generally thought of as being "non progressive", differently from non-alcoholic steatohepatitis, which increases in severity due to the presence of apoptosis ...
Contaldo Franco, Pasanisi Fabrizio, Chianese Domenico, Di Minno Matteo N, Tarantino Marianna, Riccio Antonio, Conca Paolo, Tarantino Giovanni, Scopacasa Francesco, Capone Domenico   +9 more
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Transforming growth factor beta-1 (TGF-β1) expression in patients with adenomyosis [PDF]

Revista Brasileira de Ginecologia e Obstetrícia
Objective: To compare Transforming growth factor beta-1 (TGF-β1) expression in patients with and without adenomyosis. Methods: A prospective design was performed including 49 patients submitted to hysterectomy.
Andreia Jacobo, Renata Fogaça Borges, Carlos Augusto Bastos de Souza, Vanessa Krebs Genro, João Sabino Cunha-Filho   +4 more
doaj   +1 more source

Transforming growth factor-β1 and TGF-β2 act synergistically in the fibrotic pathway in oral submucous fibrosis: An immunohistochemical observation

Indian Journal of Medical and Paediatric Oncology, 2015
Background and objectives: Oral Submucous Fibrosis (OSF) is a potentially malignant oral disorder which leads to fibrosis of the oral mucosa and has a high rate of malignant transformation.
Venkatesh Viswanath Kamath, Shruti Krishnamurthy, Krishnanand P Satelur, Komali Rajkumar   +3 more
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The recombinant proregion of transforming growth factor beta1 (latency-associated peptide) inhibits active transforming growth factor beta1 in transgenic mice. [PDF]

Proceedings of the National Academy of Sciences, 1996
All three isoforms of transforming growth factors beta (TGF-betal, TGF-beta2, and TGF-beta3) are secreted as latent complexes and activated extracellularly, leading to the release of the mature cytokines from their noncovalently associated proregions, also known as latency-associated peptides (LAPs).
E P, Böttinger, V M, Factor, M L, Tsang, J A, Weatherbee, J B, Kopp, S W, Qian, L M, Wakefield, A B, Roberts, S S, Thorgeirsson, M B, Sporn   +9 more
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Differences in Hypertrophic Scar Fibroblasts according to Scar Severity: Expression of Transforming Growth Factor beta1 at the mRNA and Protein Levels [PDF]

Archives of Aesthetic Plastic Surgery, 2015
Background Hypertrophic scars result from excessive collagen deposition and increased transforming growth factor beta-1 (TGF-beta1) levels. We hypothesized that the expression of TGF-beta1 mRNA and protein would increase with the clinical severity of ...
Se Young Kim, Seung Min Nam, Eun Soo Park, Yong Bae Kim   +3 more
doaj   +1 more source

Association between Genetic Variants of Transforming Growth Factor-β1 and Susceptibility of Pneumoconiosis: A Meta-analysis

Chinese Medical Journal, 2017
Background: Transforming growth factor-beta 1 (TGF-β1) and gene variants have been extensively studied in various human diseases. For example, TGF-β1 polymorphisms were associated with fibrosis and pneumoconiosis, but the data remained controversial. The
Chang-Wen Deng, Xing-Xing Zhang, Jin-Huan Lin, Li-Fei Huang, Yu-Lan Qu, Chong Bai   +5 more
doaj   +1 more source

Genetic control of the circulating concentration of transforming growth factor type beta1 [PDF]

Human Molecular Genetics, 1999
The concentration of transforming growth factor beta (TGF-beta) in plasma has been correlated with the development of several diseases, including atherosclerosis and certain forms of cancer. However, the mechanisms that control the concentration of TGF-beta in plasma are poorly understood. In a study of 170 pairs of female twins (average age 57.7 years)
D J, Grainger, K, Heathcote, M, Chiano, H, Snieder, P R, Kemp, J C, Metcalfe, N D, Carter, T D, Spector   +7 more
openaire   +2 more sources

Smad4 and ERK2 stimulated by transforming growth factor beta1 in rhabdomyosarcoma

Chinese Medical Journal, 2007
Transforming growth factor beta (TGF-beta) plays an essential role in the regulation of normal physiologic processes of cells. TGF-beta has been shown to regulate several mitogen-activated protein kinases (MAPK) pathways in several epithelial cells. However, the effects of TGF-beta on soft tissue sarcoma are seldom reported.
Hua, Guo, Hong-ying, Zhang, Shou-li, Wang, Lü, Ye, Guang-hua, Yang, Hong, Bu   +5 more
openaire   +2 more sources

Shen-Kang protects against tacrolimus-induced renal injury [PDF]

The Korean Journal of Internal Medicine, 2019
Background/Aims Evidence suggests that Shen-Kang (SK), a traditional Chinese herbal medicine, protects against various types of renal injury. In this study, we evaluated whether SK treatment confers renoprotection in a rat model of chronic tacrolimus ...
Long Ye Zhang, Jian Jin, Kang Luo, Shang Guo Piao, Hai Lan Zheng, Ji Zhe Jin, Sun Woo Lim, Bum Soon Choi, Chul Woo Yang, Can Li   +9 more
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Effect of EDTA on TGF-β1 released from the dentin matrix and its influence on dental pulp stem cell migration

Brazilian Oral Research
: Bioactive molecules stored in dentin, such as transforming growth factor beta1 (TGF-b1), may be involved in the signaling events related to dental tissue repair.
Lidiany Freitas GONÇALVES, Ana Paula FERNANDES, Leopoldo COSME-SILVA, Fabio Antonio COLOMBO, Natália Silva MARTINS, Thais Marchini OLIVEIRA, Tomaz Henrique ARAUJO, Vivien Thiemy SAKAI   +7 more
doaj   +1 more source