Results 61 to 70 of about 13,909 (174)
PLoS ONE, 2009 BackgroundTGF-beta1 is involved in cardiac remodeling through an auto/paracrine mechanism. The contribution of TGF-beta1 from plasmatic source to pressure overload myocardial remodeling has not been analyzed.
Ana V Villar +7 more
doaj +1 more source
Small, Volume 22, Issue 18, 25 March 2026.We introduce a versatile 3D platform that recreates key physical and biological features of the human bone marrow. By integrating tunable silk biomaterials, stromal cells, and human hematopoietic progenitors, the model captures both healthy and diseased microenvironments, analysis of blood formation, and its disruption in pathological conditions ...
Christian A. Di Buduo +13 more
wiley +1 more source
Small Structures, Volume 7, Issue 3, March 2026.Here, we report a CD44‐targeted antioxidant nanoplatform based on chondroitin sulfate‐functionalized MoS2 nanosheets (CLM NSs). In a murine pulmonary fibrosis model, CLM NSs achieve lesion‐specific accumulation, scavenge reactive oxygen/nitrogen species, and inhibit fibroblast activation and epithelial‐mesenchymal transition by blocking the ROS‐STAT1 ...
Wencheng Gong +7 more
wiley +1 more source
Prognostic value of fetal growth and prenatal functional echocardiography in tetralogy of FALLOT
Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 3, Page 479-491, March 2026.First demonstration that fetal growth and pulmonary peak velocity at third trimester are independent predictors of postnatal outcome in Tetralogy of Fallot. This may enhance the accuracy of prenatal counseling and facilitate more individualized planning for delivery and neonatal care. Abstract Introduction Tetralogy of Fallot (ToF) shows variability in
Laura Nogué +17 more
wiley +1 more source
Ursolic acid inhibits epithelial-mesenchymal transition in vitro and in vivo
Pharmaceutical Biology, 2019 Context: Ursolic acid (UA; 3β-hydroxy-urs-12-en-28-oic acid), one of the pentacyclic triterpenoids found in various plants and herbs, possesses some beneficial effects under pathological conditions, including combating hepatic fibrosis.
Chang-Geng Xu +3 more
doaj +1 more source
Brazilian Archives of Biology and Technology, 2015 Hematological malignancies (HM) are a group of neoplastic diseases that arise from hematologic cell lineages. Transforming growth factor beta 1 (TGFβ1) is shown to negatively regulate normal and malignant hematopoiesis and, in immunological context, to ...
Glauco Akelinghton Freire Vitiello +5 more
doaj +1 more source
BMC Cancer, 2007 Background AIDS-related non-Hodgkin's lymphoma (AIDS-NHL) is the second most frequent cancer associated with AIDS, and is a frequent cause of death in HIV-infected individuals. Experimental analysis of AIDS-NHL has been facilitated by the availability of
Levy Laura S +2 more
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Cellular Physiology and Biochemistry, 2013 Background/Aims: In the current study we examined if the adipocytokine, visfatin, alters connexin-mediated intercellular communication in proximal tubule-derived epithelial cells.
Claire E. Hills +3 more
doaj +1 more source
Indonesian Biomedical Journal, 2009 BACKGROUND: Vascular remodelling was an adaptive process of the vascular wall that occurred in response to long-term changes in hemodynamic conditions that contribute to the changes of the vascular structure and the pathophysiology of vascular disease ...
Johnson Wijaya +2 more
doaj +1 more source
Moxibustion enables protective effects on rheumatoid arthritis-induced myocardial injury transforming growth factor beta1 signaling and metabolic reprogramming. [PDF]
J Tradit Chin Med, 2023 Miao W, Yan Z, Hui Z, Hongfang Z.
europepmc +1 more source