Results 71 to 80 of about 41,942 (251)

Irisin Regulates the Functions of Hepatic Stellate Cells [PDF]

Endocrinology and Metabolism, 2020
Background Hepatic stellate cells (HSCs) are known to play a fundamental role in the progression of liver fibrosis. Once HSCs are activated, they are involved in proliferation, migration, and contractility which are characteristics of liver fibrogenesis.
Hanh Nguyen Dong, So Young Park, Cong Thuc Le, Dae-Hee Choi, Eun-Hee Cho   +4 more
doaj   +1 more source

ECM‐Stiffness Mediated Persistent Fibroblast Activation Requires Integrin and Formin Dependent Chromatin Remodeling

Advanced Science, EarlyView.
Prolonged exposure to stiff extracellular matrix drives cancer‐associated fibroblasts into a persistently activated myofibroblast state. Two parallel pathways are identified: β1 integrin activation smoothens the nuclear lamina to reduce lamin–chromatin contacts, while the formin mDia2 regulates nuclear actin to alter chromatin organization.
Swathi Packirisamy, Oscar André, Zhimeng Fan, Pontus Nordenfelt, Vinay S Swaminathan   +4 more
wiley   +1 more source

Contractile properties of fibroblasts derived from primary frozen shoulder and effects of TGF beta 1 stimulation [PDF]

, 2006
INTRODUCTION: Primary Frozen Shoulder (PFS) is a debilitating disease of unknown aetiology. There is fibrosis and contracture of the coracohumeral ligament, tissues of the rotator interval and the glenohumeral ligaments, leading to restrictive shoulder ...
Bains, M, Lambert, S, Mudera, V
core  

The roles of endoglin gene in cerebrovascular diseases. [PDF]

, 2017
Endoglin (ENG, also known as CD105) is a transforming growth factor β (TGFβ) associated receptor and is required for both vasculogenesis and angiogenesis.
Ma, Li, Su, Hua, Zhang, Rui, Zhu, Wan
core   +2 more sources

A synthetic peptide from transforming growth factor beta type III receptor inhibits liver fibrogenesis in rats with carbon tetrachloride liver injury [PDF]

, 2003
Transforming growth factor beta1 (TGF-beta1) is a pleiotropic cytokine, which displays potent profibrogenic effects and is highly expressed in fibrotic livers.
Blanco, G. (Gemma), Borras-Cuesta, F. (Francisco), Bustos, M. (Matilde), Castilla-Cortazar, I. (Inma), Dotor, J. (Javier), Ezquerro, I.J. (Ignacio José), Greenwel, P. (Patricia), Lasarte, J.J. (Juan José), Lechuga, M.C.G. (María del Carmen G.), Peñuelas-Sanchez, I. (Ivan), Prieto, J. (Jesús), Rodriguez-Ortigosa, C.M. (Carlos M.), Rojkind, M. (Marcos)   +12 more
core  

Thirty Years of Autologous Platelet Concentrates: From Platelet‐Rich Plasma to Platelet‐Rich Fibrin

Journal of Periodontal Research, EarlyView.
This review highlights the 30 years of evolution of APCs, with a focus on their clinical applications and recent technological advancements. ABSTRACT Nearly three decades have now passed since autologous platelet concentrates (APCs) were introduced into clinical practice.
Richard J. Miron, Nathan E. Estrin, Paras Ahmad, Nima Farshidfar, Masako Fujioka‐Kobayashi, Yufeng Zhang, Mario Romandini, Reinhard Gruber   +7 more
wiley   +1 more source

T Cell Death and Transforming Growth Factor β1 [PDF]

The Journal of Experimental Medicine, 2001
The TGF-β family comprises many cytokines involved in the control of cell fate 1. Some of these have been shown to control cell death. For instance, at least one of the members of the BMP subfamily of the TGF-β family is required in interdigital death, a classical model of developmentally programmed cell death 2.
P, Golstein, A H, Wyllie
openaire   +2 more sources

Transforming growth factor beta-1 in patients with hypertension who had COVID-19

Medičnì Perspektivi
Post-covid syndrome is a multisystem disease. The totality of disorders of organs and systems, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causes significant damage to human health for a long time, especially if the patient ...
O.V. Kuryata , O.S. Mytrokhina, O.I. Stadnyk   +2 more
doaj   +1 more source

Curcumin Nanoformulations for Dermatological Applications: From Nutraceuticals to Nanocarriers

Food Frontiers, Volume 7, Issue 3, May 2026.
Nanotechnology‐based delivery platforms enhance the cutaneous administration of curcumin. Loading free curcumin into polymeric micelles, metal‐based nanoparticles, nanogels/hydrogels, liposomes, polymeric nanoparticles, or nanoemulsions/nanocrystals helps address its low solubility, poor stability and limited skin permeation. As a result, these systems
Stephany Celeste Gutiérrez‐Ruiz, Alejandra Romero‐Montero, Hector Hernández‐Parra, Sheila I. Peña‐Corona, Héctor Adrián García‐Gasca, Katya Carbone, Fabio Gervasi, Shivaprasad Shetty Mangalpady, Rajesh Kaverikana, Mariia Shanaida, Volodymyr Shanaida, Daniela Calina, Javad Sharifi‐Rad, Gerardo Leyva‐Gómez   +13 more
wiley   +1 more source

Hyaluronan Regulates Transforming Growth Factor-β1 Receptor Compartmentalization [PDF]

Journal of Biological Chemistry, 2004
Transforming growth factor-beta1 (TGF-beta1) is a key cytokine involved in the pathogenesis of fibrosis in many organs. We previously demonstrated in renal proximal tubular cells that the engagement of the extracellular polysaccharide hyaluronan with its receptor CD44 attenuated TGF-beta1 signaling.
Takafumi, Ito, John D, Williams, Donald J, Fraser, Aled O, Phillips   +3 more
openaire   +2 more sources