Results 81 to 90 of about 9,295,419 (200)

Rhodostomin Inhibits the Transforming Growth Factor-Beta1- Enhanced Adhesion

open access: yes, 2008
We have investigated the effect of transforming growth factor-beta1 (TGF- beta1) on the in vitro adhesion activity of the rat osteosarcoma cell lines (ROS 17/2.8) to extracellular matrix substrata, including fibronectin, type I and IV collagen, as well ...
楊榮森;黃德富   +1 more
core  

Growth regulation of simian and human AIDS-related non-Hodgkin's lymphoma cell lines by TGF-β1 and IL-6

open access: yesBMC Cancer, 2007
Background AIDS-related non-Hodgkin's lymphoma (AIDS-NHL) is the second most frequent cancer associated with AIDS, and is a frequent cause of death in HIV-infected individuals. Experimental analysis of AIDS-NHL has been facilitated by the availability of
Levy Laura S   +2 more
doaj   +1 more source

Patients with hereditary hemorrhagic telangiectasia have increased plasma levels of vascular endothelial growth factor and transforming growth factor-beta1 as well as high ALK1 tissue expression

open access: yesHaematologica, 2005
BACKGROUND AND OBJECTIVES: Hereditary hemorrhagic telangiectasia (HHT), an inherited vascular dysplasia, is caused by mutations in endoglin or activin receptor-like kinase (ALK)-1.
H Sadick   +6 more
doaj  

Visfatin Reduces Gap Junction Mediated Cell-to-Cell Communication in Proximal Tubule-Derived Epithelial Cells

open access: yesCellular Physiology and Biochemistry, 2013
Background/Aims: In the current study we examined if the adipocytokine, visfatin, alters connexin-mediated intercellular communication in proximal tubule-derived epithelial cells.
Claire E. Hills   +3 more
doaj   +1 more source

Hyaluronan regulates transforming growth factor-beta1 receptor compartmentalization

open access: yes, 2004
Transforming growth factor-beta1 (TGF-beta1) is a key cytokine involved in the pathogenesis of fibrosis in many organs. We previously demonstrated in renal proximal tubular cells that the engagement of the extracellular polysaccharide hyaluronan with its
Ito, Takafumi   +3 more
core   +1 more source

Irisin Attenuates Hepatic Stellate Cell Activation and Liver Fibrosis in Bile Duct Ligation Mice Model and Improves Mitochondrial Dysfunction [PDF]

open access: yesEndocrinology and Metabolism
Background Liver fibrosis is a common outcome of chronic liver disease and is primarily driven by hepatic stellate cell (HSC) activation. Irisin, a myokine released during physical exercise, is beneficial for metabolic disorders and mitochondrial ...
Thuy Linh Lai   +9 more
doaj   +1 more source

Quercetin inhibits transforming growth factor β1-induced epithelial–mesenchymal transition in human retinal pigment epithelial cells via the Smad pathway

open access: yesDrug Design, Development and Therapy, 2018
Wenting Cai,1,* Donghui Yu,1,* Jiaqi Fan,2 Xiuwei Liang,3 Huizi Jin,1 Chang Liu,2 Meijiang Zhu,1 Tianyi Shen,1 Ruiling Zhang,1 Weinan Hu,4 Qingquan Wei,1 Jing Yu1,5 1Department of Ophthalmology, Shanghai Tenth People’s Hospital Affiliated with ...
Cai W   +11 more
doaj  

Latent Transforming Growth Factor-beta1 Functionalised Electrospun Scaffolds Promote Human Cartilage Differentiation: Towards an Engineered Cartilage Construct

open access: yesArchives of Plastic Surgery, 2013
Background To overcome the potential drawbacks of a short half-life and dose-related adverse effects of using active transforming growth factor-beta 1 for cartilage engineering, a cell-mediated latent growth factor activation strategy was developed ...
Erh-Hsuin Lim   +3 more
doaj   +1 more source

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