Results 91 to 100 of about 9,295,419 (200)

Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2020
Angelamellisy Revelian Ndibalema,1,2 Deo Kabuye,3,4 Si Wen,1 Lulu Li,1 Xin Li,1 Qiuling Fan1 1Department of Nephrology, The First Hospital of China Medical University, Shenyang 110001, People’s Republic of China; 2Kairuki Hospital, Dar es Salaam ...
Ndibalema AR   +5 more
doaj  

Intracellular expression of tumor necrosis factor alpha, interleukin 6, transforming growth factor beta1 and interleukin 10 by monocytes from healthy individuals distributed in function of the -238 promotor gene polymorphism.

open access: yes, 2013
Basal and LPS-stimulated concentration of tumor necrosis factor alpha, interleukin 6, transforming growth factor beta1 and interleukin 10 on supernatants of monocyte cultures. Abbreviations: TNF-α tumor necrosis factor alpha. IL-6, interleukin 6. TGF-β1,
Clotilde Fernández-Gutiérrez (427100)   +5 more
core   +1 more source

Adeno-Associated Vector mediated gene transfer of Transforming Growth Factor-beta1 to normal and osteoarthritic human chondrocytes stimulates cartilage anabolism

open access: yesEuropean Cells & Materials, 2005
The objective of the present study was to investigate whether cartilage anabolism in human primary osteoarthritic chondrocytes could be improved by adeno-associated virus (AAV) vector-mediated gene transduction of transforming growth factor TGF-beta1 ...
Ulrich-Vinther M.   +4 more
doaj  

ERK, p38, and Smad signaling pathways differentially regulate transforming growth factor-beta1 autoinduction in proximal tubular epithelial cells

open access: yes, 2006
Transforming growth factor (TGF)-beta1 is a mediator of the final common pathway of fibrosis associated with progressive renal disease, a process in which proximal tubular cells (PTCs) are known to play an important part. The aim of the current study was
Donald Fraser   +5 more
core   +1 more source

Blocking TSP1 Ameliorates Diabetes Mellitus-Induced Erectile Dysfunction by Inhibiting the TGF-β/SMAD Pathway

open access: yesThe World Journal of Men's Health
Purpose: To examine the role and mechanism of thrombospondin-1 (TSP1) in the development of fibrosis in diabetes mellitus- induced erectile dysfunction (DMED). Materials and Methods: DMED was induced by intraperitoneal streptozotocin injection.
Mancheng Xia   +11 more
doaj   +1 more source

Factor de crecimiento transformante beta-1: estructura, función y mecanismos de regulación en cáncer Transforming growth factor beta-1: structure, function and regulation mechanisms in cancer

open access: yesSalud Pública de México, 2001
El factor de crecimiento transformante beta-1 (TGF-beta1) es sintetizado por muchas estirpes celulares como linfocitos, macrófagos y células dendríticas, y su expresión regula de manera autócrina o parácrina la diferenciación, proliferación y el estado ...
Oscar Peralta-Zaragoza   +2 more
doaj  

Transforming growth factor-β1 gene polymorphism in psoriasis vulgaris

open access: yesClinical, Cosmetic and Investigational Dermatology, 2018
Heba H El-hadidi,1 Akmal S Hassan,1 Ghada El-hanafy,1 Khalda S Amr,2 Sameh F Abdelmesih,3 Mahmoud F Abdelhamid3 1Department of Dermatology, Kasr Al-Ainy University Hospitals, Cairo University, Giza, Egypt; 2Department of Molecular Genetics, National ...
El-hadidi HH   +5 more
doaj  

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