International Journal of Nanomedicine, 2012 Wen Wen Deng*, Xia Cao*, Miao Wang*, Rui Qu, Wei Yan Su, Yan Yang, Ya Wei Wei, Xi Ming Xu, Jiang Nan YuDepartment of Pharmaceutics, School of Pharmacy and Center for Nano Drug/Gene Delivery and Tissue Engineering, Jiangsu University, Zhenjiang, People ...
Deng WW +8 more
doaj +1 more source
Immunological studies of chronic ocular toxoplasmosis : up-regulation of major histocompatibility complex class I and transforming growth factor beta and a protective role for interleukin-6 [PDF]
, 2001 A murine model was used to characterize the local immune and inflammatory response during ocular toxoplasmosis. Major histocompatibility complex (MHC) class I, normally expressed at low levels in immune-privileged sites such as the eye, was up-regulated ...
Byrne, N. +6 more
core +4 more sources
Bacterial meningitis: the role of transforming growth factor-Beta in innate immunity and secondary brain damage [PDF]
, 2007 Project 6 of the NCCR 'Neural Plasticity and Repair' focuses on mechanisms of immunity and tissue damage in autoimmune and infectious diseases of the central nervous system (CNS).
Malipiero, U +7 more
core +1 more source
Activation of transforming growth factor beta by malaria parasite-derived metalloproteinases and a thrombospondin-like molecule [PDF]
, 2003 Much of the pathology of malaria is mediated by inflammatory cytokines (such as interleukin 12, interferon gamma, and tumor necrosis factor alpha), which are part of the immune response that kills the parasite.
Riley, Eleanor M +14 more
core +1 more source
Transforming growth factor-beta receptor mutations and pulmonary arterial hypertension in childhood [PDF]
, 2005 BACKGROUND: Pulmonary arterial hypertension (PAH) is a potentially fatal vasculopathy that can develop at any age. Adult-onset disease has previously been associated with mutations in BMPR2 and ALK-1.
Haworth, SG +22 more
core +1 more source
Transforming growth factor-beta and the glomerular filtration barrier
Kidney Research and Clinical Practice, 2013 The increasing burden of chronic kidney disease worldwide and recent advancements in the understanding of pathologic events leading to kidney injury have opened up new potential avenues for therapies to further diminish progression of kidney disease by ...
Ayesha Ghayur, Peter J. Margetts
doaj +1 more source
Transforming Growth Factor-Beta (TGFβ) Signaling Pathway in Cholangiocarcinoma
Cells, 2019 Cholangiocarcinoma is a deadly cancer worldwide, associated with a poor prognosis and limited therapeutic options. Although cholangiocarcinoma accounts for less than 15% of liver primary cancer, its silent nature restricts early diagnosis and prevents ...
Panagiotis Papoutsoglou +2 more
doaj +1 more source
International Journal of Ophthalmology, 2017 AIM: To report a phenotypic variant pedigree of lattice corneal dystrophy (LCD) associated with two mutations, R124C and A546D, in the transforming growth factor beta-induced gene (TGFBI).
Wen-Ping Cao,
doaj +1 more source
Arthritis Research & Therapy, 2023 Background Transforming growth factor beta (TGF-β1) is a multifunctional cytokine that has anti-inflammatory and immunosuppressive effects. TGF-β1 has been linked to cardiovascular disease in the general population. The immunosuppressive effect of TGF-β1
Fuensanta Gómez-Bernal +7 more
doaj +1 more source
TGF beta 1 attenuates expression of prolactin and IGFBP-1 in decidualized endometrial stromal cells by both SMAD-dependent and SMAD-independent pathways [PDF]
, 2010 Background: Decidualization (differentiation) of the endometrial stromal cells during the secretory phase of the menstrual cycle is essential for successful implantation.
Jones Marius +30 more
core +1 more source