Results 21 to 30 of about 9,555,806 (265)

Bone remodeling at microscrew interface near extraction site in the beagle dog mandible-histologic and immunohistochemical analyses

open access: yesJournal of Applied Oral Science, 2013
Extraction is often used as part of orthodontic therapy, and good control of anchorage is a key step after extraction. Although microscrews can be implanted close to the extraction site in order to achieve orthodontic support, the efficiency of bone ...
Guangxi Wei   +5 more
doaj   +1 more source

Transforming growth factor-β: Biology and application to cancer therapy [PDF]

open access: yesArchive of Oncology, 2009
Transforming growth factor-β (TGF-β), an extensively investigated cytokine, plays a very important role in promoting the spread of cancers in the body, and can play a direct role in facilitating metastasis.
Ivanović Vesna
doaj   +1 more source

A Novel Megakaryocyte Subpopulation Poised to Exert the Function of HSC Niche as Possible Driver of Myelofibrosis

open access: yesCells, 2021
Careful morphological investigations, coupled with experimental hematology studies in animal models and in in vitro human cultures, have identified that platelets are released in the circulation by mature megakaryocytes generated by hematopoietic stem ...
Anna Rita Migliaccio
doaj   +1 more source

Epigenetic downregulation of human disabled homolog 2 switches TGF-beta from a tumor suppressor to a tumor promoter [PDF]

open access: yes, 2010
The cytokine TGF-beta acts as a tumor suppressor in normal epithelial cells and during the early stages of tumorigenesis. During malignant progression, cancer cells can switch their response to TGF-beta and use this cytokine as a potent oncogenic factor;
Hiller, L   +133 more
core   +1 more source

Transforming growth factor beta (TGF-β) in adolescent chronic fatigue syndrome

open access: yesJournal of Translational Medicine, 2017
Background Chronic fatigue syndrome (CFS) is a prevalent and disabling condition among adolescent. The disease mechanisms are unknown. Previous studies have suggested elevated plasma levels of several cytokines, but a recent meta-analysis of 38 articles ...
Vegard Bruun Wyller   +3 more
doaj   +1 more source

TGF-beta1 in breast cancer-estrogen regulation [PDF]

open access: yesArchive of Oncology, 2002
TGF-beta1 is a pluripotent cytokine with diverse effects in the normal development of mammary glands, and in the development of malignant tumors of the breast.
Todorović-Raković Nataša   +7 more
doaj   +1 more source

بررسی اثر کلسترول بر فعال‌سازی مسیر سیگنالینگ TGF-β / Smad3C در سلول‌های ستاره‌ای کبد و نقش آن در پیشرفت فیبروژنز کبدی [PDF]

open access: yesمجله دانشکده پزشکی اصفهان, 2021
مقدمه: فیبروز کبدی، اغلب به فعال شدن سلول‌های ستاره‌ای کبد (Hepatic stellate cells یا HSCs) و تشکیل بیش از حد زخم در کبد نسبت داده می‌شود؛ چرا که این سلول‌ها باعث تولید بیش از حد ماتریکس خارج سلولی می‌شوند.
doaj   +1 more source

Bisacurone gel ameliorated burn wounds in experimental rats via its anti-inflammatory, antioxidant, and angiogenic properties [PDF]

open access: yesActa Cirúrgica Brasileira, 2023
Purpose: To investigate putative mechanism of wound healing for chitosan-based bisacurone gel against secondary burn wounds in rats. Methods: A second-degree burn wound with an open flame using mixed fuel (2 mL, 20 seconds) was induced in Sprague Dawley
Zengqiang Yan, Shuyan Li, Zhenzhong Gong
doaj   +1 more source

The role of transforming growth factor beta in tertiary dentinogenesis

open access: yesDental Journal, 2008
The most visible repair response to pulp injury is the deposition of a tertiary dentin matrix over the dentinal tubules of the primary or secondary dentin.
Tetiana Haniastuti   +2 more
doaj   +1 more source

Inhibition of Integrin αvβ6 Activation of TGF‐β Attenuates Tendinopathy

open access: yesAdvanced Science, 2022
Tendinopathy is a common tendon disorder that causes pain and impairs function. It is the most common reason for consultation with musculoskeletal specialists.
Xiao Wang   +11 more
doaj   +1 more source

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