Transforming growth factor-β signaling in thymic epithelial cells : its role in development, steady-state and immune reconstitution [PDF]
, 2010 The thymus constitutes the primary lymphoid organ responsible for the generation of naïve T cells. Its stromal compartment is composed of a scaffold of different subsets of epithelial cells that provide soluble and membrane-bound molecules essential for ...
Hauri-Hohl, Mathias Martin
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Journal of the Egyptian Women’s Dermatologic Society, 2022 Background Systemic sclerosis is characterized by extracellular matrix overproduction by activated fibroblasts. It was reported that microRNAs (miRNAs) participate in the regulation of processes that drive fibrosis, which include transforming growth ...
Mohammed Hassan Mohammed +4 more
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Transforming growth factor beta 1, a cytokine with regenerative functions
Neural Regeneration Research, 2016 We review the biology and role of transforming growth factor beta 1 (TGF-β1) in peripheral nerve injury and regeneration, as it relates to injuries to large nerve trunks (i.e., sciatic nerve, brachial plexus), which often leads to suboptimal functional ...
Wale Sulaiman, Doan H Nguyen
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Transforming growth factor-ß (TGF-ß) signaling in hematopoiesis and tumorigenesis [PDF]
, 2008 Transforming growth factor β (TGF-β) signaling regulates numerous cellular and physiological processes. Dysfunction of components of this signaling pathway leads to a wide range of diseases ranging from malignant hematopoiesis, cardiovascular disease,
Pan, Dejing
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Neural Regeneration ResearchNeuronal degeneration and inflammation are hallmark features of spinal cord injury that severely hinder functional recovery. As key regulators of the post-injury microenvironment, macrophages can promote either tissue repair or exacerbate damage.
Haiwen Feng +9 more
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Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFβ1) gene in knee and hip osteoarthritis [PDF]
, 2013 Introduction: The objective was to investigate potential gene-environment interaction between body mass index (BMI) and each of eight TGFβ1 polymorphisms in knee and hip osteoarthritis (OA).
Muthuri, Stella G. +19 more
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Transforming growth factor-beta family annotation.
, 2023 Transforming growth factor-beta family annotation.
Antonio Carlos A. Meireles-Filho (15213879) +82 more
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Recent Topics in Fibrodysplasia Ossificans Progressiva [PDF]
Endocrinology and Metabolism, 2018 Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease that is characterized by the formation of heterotopic bone tissues in soft tissues, such as skeletal muscle, ligament, and tendon.
Takenobu Katagiri +3 more
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Is telomerase reactivation associated with the down-regulatoin of TGFβ receptor-II expression in human breast cancer? [PDF]
, 2003 Background Telomerase is a ribonucleoprotein that synthesizes telomeres and plays an important role in chromosomal stability and cellular immortalisation. Telomerase activity is detectable in most human cancers but not in normal somatic cells. TGF beta (
Thomas, V +11 more
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Transforming Growth Factor Beta One and Non Alcoholic Fatty Liver Disease [PDF]
Afro-Egyptian Journal of Infectious and Endemic Diseases, 2014 Background and study aim: Hepatic steatosis reflects an imbalance between the uptake and synthesis of fatty acids by the liver and their oxidation and export. The mechanism of cell injury remains unclear. Transforming growth factor – beta 1 (TGF-β1) as a
Magy Fawzy +4 more
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