Results 81 to 90 of about 30,392 (225)

From platelets to particles: Optimizing extracellular vesicle isolation in a National Blood Centre

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives Platelet‐derived extracellular vesicles (PEVs) are submicron, membrane‐bound particles released upon platelet activation, with a recognized role in haemostasis, inflammation and immunoregulation. PEVs remain insufficiently characterized in blood products.
Y. Chintala   +5 more
wiley   +1 more source

Mother Who Experienced TRALI After a Caesarian Section on the Indication of Severe Pre-eclampsia with a Macrosomic Fetus

open access: yesAndalas Obstetrics and Gynecology Journal
Introduction: Transfusion-Related Acute Lung Injury (TRALI) is a severe, often fatal, complication of blood transfusion. Obstetric patients with severe pre-eclampsia are uniquely susceptible due to a "two-hit" mechanism, where the underlying inflammatory
Puti Fajri Lestari, Pom Harry Satria
doaj   +1 more source

Patient blood management and surgery: Impact of new surgical techniques on transfusion needs

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives Patient blood management (PBM) is a multidisciplinary approach aimed at reducing the use of blood products. It considers the patient's own blood as a valuable resource to preserve and seeks to avoid the routine use of transfusions to treat anaemia.
Francois Ansart, France Pirenne
wiley   +1 more source

Synergistic Effect of Anemia and Red Blood Cells Transfusion on Inflammation and Lung Injury

open access: yesAdvances in Hematology, 2012
Anemia and resultant red blood cell transfusion may be associated with adverse long-term clinical outcomes. To investigate the mechanism(s) responsible, we profiled inflammatory biomarkers and circulating levels of the bioactive lysophospholipid mediator
Anping Dong   +6 more
doaj   +1 more source

A quality improvement initiative to reduce inappropriate plasma transfusions across community hospitals in the Niagara region

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives Plasma transfusion is indicated for patients with coagulopathy and active bleeding or those undergoing major surgery. Appropriate use is defined by an international normalized ratio (INR) >1.7 and a dose of 3–4 units for adults.
Krista Walter   +4 more
wiley   +1 more source

Acute Lung Injury during Antithymocyte Globulin Therapy for Aplastic Anemia

open access: yesCanadian Respiratory Journal, 2009
The case of a 33-year-old man with aplastic anemia who experienced recurrent episodes of hypoxemia and pulmonary infiltrates during infusions of antithymocyte globulin (ATG) is described.
Ewan Christopher Goligher   +4 more
doaj   +1 more source

Investigating human platelet antigens and antibodies in pregnancy: An 11‐year experience from a Canadian reference laboratory

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives Foetal and neonatal alloimmune thrombocytopaenia (FNAIT) is a potentially severe immune‐mediated condition that is believed to be under‐identified in the Canadian population. The Canadian Blood Services National Platelet Immunology Reference Laboratory (NPIRL) serves as a centralized referral laboratory for FNAIT ...
Bryan Tordon   +4 more
wiley   +1 more source

TRALI-SYNDROME: DIAGNOSTICS, PREVENTION, TREATMENT

open access: yesВестник анестезиологии и реаниматологии, 2019
The lecture is devoted to transfusion-related acute lung injury (TRALI), which is rarely encountered and therefore poorly studied by clinicians. With late diagnosis and inadequate management, the injury can be fatal. In some countries, it is ranked third
M. I. Neymark
doaj   +1 more source

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