Results 11 to 20 of about 99,595 (215)

Blood transfusion reactions and institutional hemovigilance protocols: A 2-year retrospective single center audit

International Journal of Medicine and Health Development, 2023
Background: Blood transfusion reactions contribute significantly to the morbidity and mortality of both in- and outpatients in hospitals globally. Developing adequate protocols for detecting and reporting this complication is key to attaining global ...
John C Aneke, Chisom G Chigbo, Perpetua O Emeh, Francis Ifediata, Chilota C Efobi, Ugochinyere J Chilaka, Nkechinyere T Ibekwe, Theodora U Ezeh, Chiamaka B Aneke   +8 more
doaj   +1 more source

IgE- and IgG mediated severe anaphylactic platelet transfusion reaction in a known case of cerebral malaria

Asian Journal of Transfusion Science, 2013
Background: Allergic reactions occur commonly in transfusion practice. However, severe anaphylactic reactions are rare; anti-IgA (IgA: Immunoglobulin A) in IgA-deficient patients is one of the well-illustrated and reported causes for such reactions ...
B Shanthi, Bhavanadhar, Priscilla Chandran, A Krishna Prasad   +3 more
doaj   +1 more source

Acute Transfusion Reactions in a Tertiary Care Hospital: The Saudi Context

Scientific Journal of King Faisal University: Basic and Applied Sciences, 2022
Although blood transfusion is a life-saving procedure, it can be associated with complications in rare cases. An acute transfusion reaction (ATR) is a complication where recipients exhibit an adverse reaction within 24 hours of a blood transfusion.
Mohrah Alalshaikh, Sarah Abo Baker, Ammar Alsughayir, Yasser Almaki, Leenah Almass, Mohammed Alnamnakani, Alyazeed Alsaif, Abdullah Albarghash, Imran Ahad Pukhta   +8 more
doaj   +1 more source

Impact of buffy coat reduction on the severity of febrile nonhemolytic transfusion reactions with red cell components

Asian Journal of Transfusion Science, 2023
BACKGROUND: Febrile nonhemolytic transfusion reactions (FNHTRs) are the most common adverse reaction reported under the Haemovigilance Programme of India, and the use of leukodepleted blood products is recommended. The severity of the reaction may affect
Lakhvinder Singh, Nippun Prinja, Ashish Jain, Ratti Ram Sharma, Neelam Marwaha   +4 more
doaj   +1 more source

Transfusion reaction: A blind spot in autopsy

Sri Lanka Journal of Medicine, 2023
Although blood transfusion is generally safe, there are adverse events with varying severity even that can lead to death including Acute Haemolytic Transfusion Reaction (AHTR), anaphylaxis, bacterial sepsis, Transfusion Related Acute Lung Injury (TRALI ...
S. Senavirathna, S. Wijerathne
doaj   +1 more source

Transfusion Reactions in Pediatric Patients: An Analysis of 5 Years of Hemovigilance Data From a National Center for Children's Health in China

Frontiers in Pediatrics, 2021
Objective: This study aimed to describe transfusion reactions of pediatric patients from a National Center for Children's Health in China and to examine reaction incidents, reaction types by blood transfusion, and the associated blood products resulting ...
Kai Guo, Xiaohuan Wang, Huimin Zhang, Mengjian Wang, Shanshan Song, Shuxuan Ma   +5 more
doaj   +1 more source

Prospective audit of transfusion utilization trends and transfusion practices at a rural tertiary care hospital in Central India

Saudi Journal for Health Sciences, 2023
Background: In modern health-care system, practicing safe and appropriate transfusion services is essential. Care should be taken at all three phases of transfusion practices, i.e. pretransfusion, transfusion, and posttransfusion.
Vihanka Devchand Vaidya, Abhay Vilas Deshmukh, Vitaladevuni Balasubramanyam Shivkumar, Manish Arun Meshram   +3 more
doaj   +1 more source

Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy

Hepatology, EarlyView., 2022
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann, Marti Cabanes‐Creus, Moritz Ertelt, Renina Gale Navarro, Julie Lucifora, Qinggong Yuan, Karin Nien‐Huber, Ahmed Abdelrahman, Xuan‐Khang Vu, Liang Zhang, Ann‐Christin Franke, Christian Schmithals, Albrecht Piiper, Annabelle Vogt, Maria Gonzalez‐Carmona, Jochen T. Frueh, Evelyn Ullrich, Philip Meuleman, Steven R. Talbot, Margarete Odenthal, Michael Ott, Erhard Seifried, Clara T. Schoeder, Joachim Schwäble, Leszek Lisowski, Hildegard Büning   +25 more
wiley   +1 more source

Hypotensive transfusion reaction due to leukoreduced platelets

Global Journal of Transfusion Medicine, 2023
Hypotensive transfusion reaction is a distinct category of adverse sequelae of transfusion characterized by an early and abrupt onset of hypotension, typically resolving promptly upon discontinuation of the transfusion.
Ramasubramaniam Natarajan, Rajasekar Arumugam   +1 more
doaj   +1 more source

CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis

Hepatology, EarlyView., 2022
A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang, Dan Wan, Mengchen Zhu, Guihu Wang, Xurui Zhang, Na Huang, Jian Zhang, Chongyu Zhang, Qi Shang, Chen Zhang, Xi Liu, Fanfan Liang, Chunyan Zhang, Guangyao Kong, Jing Geng, Libo Yao, Shemin Lu, Yongyan Chen, Zongfang Li   +18 more
wiley   +1 more source