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Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy
Hepatology, EarlyView., 2022 Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann +25 more
wiley +1 more source
Asian Journal of Transfusion Science, 2023 BACKGROUND: Febrile nonhemolytic transfusion reactions (FNHTRs) are the most common adverse reaction reported under the Haemovigilance Programme of India, and the use of leukodepleted blood products is recommended. The severity of the reaction may affect
Lakhvinder Singh +4 more
doaj +1 more source
Serious Hazards of Transfusion (SHOT) Annual Report 1997 -1998 [PDF]
, 2023 SHOT is affiliated to the Royal College of PathologistsMAIN FINDINGS AND RECOMMENDATIONS 1. Participation, 2 .Incorrect blood component transfused incidents, 3. Immune complications of transfusion, 4. Transfusion-transmitted infections, 5.
Serious Hazards of Transfusion (SHOT)
core
CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis
Hepatology, EarlyView., 2022 A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang +18 more
wiley +1 more source
Frontiers in Pediatrics, 2021 Objective: This study aimed to describe transfusion reactions of pediatric patients from a National Center for Children's Health in China and to examine reaction incidents, reaction types by blood transfusion, and the associated blood products resulting ...
Kai Guo +5 more
doaj +1 more source
Acute Transfusion Reaction [PDF]
Nephron, 2008 Acute kidney failure can result in hemolytic anemia, serum sickness due to the application of incompatible blood types which are most exposed to the patients underwent surgery. In the treatment plasnapheresis, glucocorticoids and blood derivatives correct blood group should be applied.
Galešić, Krešimir +1 more
openaire +2 more sources
Prion diseases are efficiently transmitted by blood transfusion in sheep [PDF]
, 2008 The emergence of variant Creutzfeld-Jakob disease, following on from the bovine spongiform encephalopathy (BSE) epidemic, led to concerns about the potential risk of iatrogenic transmission of disease by blood transfusion and the introduction of costly ...
Foster, J. +8 more
core +1 more source
A Case of Washed Platelet Transfusion in a Patient with History of Recurrent Transfusion Reaction Ji Yeon Sohn1, Joo-Hyoung Hwang1, Hyang-lae Lee1 [PDF]
, 2015 Anaphylactic transfusion reaction is caused by deficiency of certain protein(s) in the recipient. We report on the experience of platelet count recovery using washed platelets for transfusion in a patient who developed an anaphylactic transfusion ...
김신영
core +1 more source
Transfusion-related acute lung injury – afrequently undiagnosed reaction following transfusion ofblood components [PDF]
, 2015 Transfusion-related acute lung injury is the leading cause of mortality following transfusion of blood components. Its characteristic feature is acute hypoxaemia during or 6 hours after transfusion.
Łata, Anna +3 more
core +1 more source
, 2022 Background: Hypotensive transfusion reaction (HyTR) is rare. It is characterized by a rapid onset of hypotension during transfusion, which usually resolves quickly upon cessation of transfusion.
권순성, 김신영, 김현옥
core +1 more source