Results 61 to 70 of about 59,146 (195)
Macromolecular Bioscience, EarlyView.Heparin is postulated to possess antitumor properties‐ beyond its anticoagulative activities in oncology, but disclosure of targeted activities is complicated by heparins structural variabilities as natural glycosaminoglycans. Here, synthetic noncarbohydrate polymers are presented with tuneable structures as heparin mimetics in in‐vitro‐approaches for ...
Katrin Nekipelov +12 more
wiley +1 more source
Polypept(o)ide‐Based Core–Shell Bottlebrush Polymers: A Versatile Platform for Drug Encapsulation
Macromolecular Bioscience, EarlyView.This study developed polypept(o)ide‐based core–shell brushes (CSBs) with tunable sizes (Rh: 17–70 nm) for hydrophobic drug delivery. CSBs achieved 10% dasatinib loading through π–π interactions, enabling sustained release over 72 h. Notably, CSB‐dasatinib complexes showed comparable cell viability reduction to the free drug in U‐87 MG cells ...
Bonan Zhao +6 more
wiley +1 more source
Traditional Chinese Medicine Properties and Microcalorimetry: BioScience Evaluation
Med Research, EarlyView.ABSTRACT The properties theory of traditional Chinese medicine (TCM), characterized by cold, hot, warm, and cool four properties, is fundamental to its development, distinguishing it from natural, botanical, and chemical medicines. However, despite its significance, there is no unified theoretical definition, bioscientific characterization, or ...
Qiang Li +9 more
wiley +1 more source
Dietary Adaptation of Non‐Heme Iron Absorption in Vegans: A Controlled Trial
Molecular Nutrition &Food Research, EarlyView.This study investigated how non‐heme iron from plant foods is absorbed in vegans compared to omnivores. After consuming pistachios, vegans showed a greater increase in blood iron levels. This may reflect physiological adaptations in iron metabolism, including lower hepcidin levels that promote iron absorption.
Miguel López‐Moreno +6 more
wiley +1 more source
Real‐time fetal brain and placental T2* mapping at 0.55T MRI
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose To provide real‐time, organ‐specific quantitative information — specifically placental and fetal brain T2 * — to optimize and personalize fetal MRI examinations. Methods A low‐latency setup enables real‐time processing, including segmentation, T2* fitting, and centile calculation.
Jordina Aviles Verdera +9 more
wiley +1 more source
Prenatal Diagnosis, EarlyView.ABSTRACT Prenatal exome sequencing (ES) can establish rare genetic diagnoses in a fetus but may also lead to occult genetic diagnosis in a biological parent. We present a case of dual fetal and maternal diagnosis by prenatal ES, in a fetus with unexplained anemia and in a pregnant patient with sickle cell disease (SCD) and recurrent unexplained hypoxia.
Matthew A. Shear +6 more
wiley +1 more source
Prenatal Diagnosis, EarlyView.ABSTRACT This manuscript summarises the debate held at the 2024 annual meeting of The International Society for Prenatal Diagnosis (ISPD). Experts discussed whether all fetuses undergoing fetal therapy should undergo exome sequencing. Arguments in favor included that, with increasing experience and better clinical availability, exome sequencing can ...
Teresa N. Sparks +2 more
wiley +1 more source
Pediatric Discovery, EarlyView.Phyllanthus urinaria L can alleviate cisplatin‐induced acute kidney injury by inhibiting inflammation, apoptosis and oxidative stress. ABSTRACT Acute kidney injury (AKI) is a prevalent and serious clinical challenge with limited specific treatments.
Qitong Guo +8 more
wiley +1 more source