Results 181 to 190 of about 60,792 (253)
Abstract Background and Objectives Rh is among the most important and highly polymorphic blood group systems due to the proximity of the RHD and RHCE genes, which encode numerous highly immunogenic antigens. However, in areas of Saudi Arabia with a high prevalence of hemoglobinopathy, the molecular characteristics of RHD and RHCE variations are lacking.
Maymoon M. Madkhali +14 more
wiley +1 more source
Abstract Solid organ transplant is associated with high rates of anaemia and transfusion, but there is little comparative data on interventions such as erythropoietin‐stimulating agents (ESAs) and intravenous (IV) iron. We conducted a systematic review examining the association of ESAs and IV iron with outcomes in adults undergoing solid organ ...
Frank Lee +13 more
wiley +1 more source
Abstract Background Screening blood donations for HEV RNA mitigates the risk of transfusion‐transmitted HEV infection (TT‐HEV), a recognised blood safety issue in Europe. This study reports the findings of government‐funded HEV RNA blood donation screening 2016–2022 and includes an estimate of residual risk. Method Donation samples were universally and
Niamh O'Flaherty +6 more
wiley +1 more source
Pilot study to understand and compare challenges being faced in reporting of transfusion reactions in various types of blood banks enrolled under Haemovigilance Programme of India. [PDF]
Bhat RA +5 more
europepmc +1 more source
Abstract Background Blood transfusion remains a cornerstone in the management of sickle cell disease (SCD); however, it is frequently complicated by red cell alloimmunisation. A significant debate persists within the scientific community regarding the optimal strategy to mitigate this risk: the traditional, pragmatic approach of serologic phenotyping ...
Christiane Ruffato Carminati +6 more
wiley +1 more source
Incidence and risk factors of transfusion reactions in postpartum blood transfusions. [PDF]
Thurn L +3 more
europepmc +1 more source
Abstract Objectives To evaluate laboratory investigations for micronutrient deficiencies as the cause of anaemia prior to first‐time red blood cell transfusions in the medical emergency department (ED) of a large academic hospital. Background The ED is often the first point of contact for acutely ill anaemic patients, yet patient blood management ...
Andrea Coetzee +5 more
wiley +1 more source
Clinical implications of imlifidase interference in antibody screening and transfusion management
Abstract Background Imlifidase has received conditional approval from the EMA for desensitizing deceased donor kidney transplant recipients. It works by cleaving IgG into F(ab′)2 and Fc fragments, thereby reducing the risk of antibody‐mediated rejection. However, its impact on diagnostic assays remains understudied. Case Report We present the case of a
Zgjim Osmani +2 more
wiley +1 more source
Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike +33 more
wiley +1 more source
Abstract Background Extremely preterm neonates often require red blood cell (RBC) transfusions derived from adult donors. These transfusions introduce adult hemoglobin into a neonatal hematopoietic system dominated by fetal hemoglobin (HbF), shifting the oxygen‐dissociation curve and increasing oxygen delivery to immature tissues.
Jip H. van Daelen +8 more
wiley +1 more source

