Results 131 to 140 of about 355,983 (382)
Effects of overexpression of jasmonic acid biosynthesis genes on nicotine accumulation in tobacco
Nicotine is naturally synthesized in tobacco roots and accumulates in leaves as a defense compound against herbivory attack. Nicotine biosynthesis pathway has been extensively studied with major genes and enzymes being isolated and functionally ...
Hongxia Chen +5 more
doaj +1 more source
Modeling Control of Invasive Fire Ants by Gene Drive
The fire ant Solenopsis invicta is characterized by exceptional invasive capabilities, rendering conventional control ineffective. Here, we explore the use of homing suppression gene drive in fire ants by developing a spatially explicit model. Overall, these results show that target population suppression requires an extended time scale, but that gene ...
Yiran Liu +3 more
wiley +1 more source
MRI of Transgene Expression: Correlation to Therapeutic Gene Expression
Magnetic resonance imaging (MRI) can provide highresolution 3D maps of structural and functional information, yet its use of mapping in vivo gene expression has only recently been explored.
Tomotsugu Ichikawa +7 more
doaj +1 more source
Early expression of a T-cell receptor beta-chain transgene suppresses rearrangement of the V gamma 4 gene segment. [PDF]
Harald von Boehmer +9 more
openalex +1 more source
This study develops a novel 3D human skeletal muscle organoid platform to study the immediate molecular effects of exercise‐like contractions. The model uncovers rapid proteomic and transcriptomic responses, resolving a fundamental paradox by demonstrating how exercise‐induced Lamtor1 coordinately activates both AMPK and mTORC1. Lamtor1 is a compelling
Ziyue Yao +9 more
wiley +1 more source
Divergent disease patterns in granulocyte-macrophage colony-stimulating factor transgenic mice associated with different transgene insertion sites. [PDF]
D Metcalf, Jeffrey G. Moore
openalex +1 more source
In vivo evidence for NMDA receptor mediated excitotoxicity in a murine genetic model of Huntington Disease [PDF]
N-methyl-D-aspartate receptor (NMDAR) mediated excitotoxicity is implicated as a proximate cause of neurodegeneration in Huntington Disease (HD). However, this hypothesis has not been tested rigorously in vivo. NMDAR NR2B-subunits are the predominant NR2
Joe Tsien +4 more
core +1 more source
Transgenics on the internet [PDF]
Richard Peters, Robert S. Sikorski
openaire +3 more sources
This study reveals the genetic and molecular mechanisms controlling the general trade‐off between phenotypic mean and plasticity of grain chalkiness in rice and identifies two major external drivers (high temperature and wide grain) and a natural major module (GCP6‐MPC5) that control this trade‐off.
Juncheng Zhang +10 more
wiley +1 more source
A dominant-negative transgene defines a role for p56lck in thymopoiesis. [PDF]
Steven D. Levin +3 more
openalex +1 more source

