Results 131 to 140 of about 355,983 (382)

Effects of overexpression of jasmonic acid biosynthesis genes on nicotine accumulation in tobacco

open access: yesPlant Direct, 2018
Nicotine is naturally synthesized in tobacco roots and accumulates in leaves as a defense compound against herbivory attack. Nicotine biosynthesis pathway has been extensively studied with major genes and enzymes being isolated and functionally ...
Hongxia Chen   +5 more
doaj   +1 more source

Modeling Control of Invasive Fire Ants by Gene Drive

open access: yesAdvanced Science, EarlyView.
The fire ant Solenopsis invicta is characterized by exceptional invasive capabilities, rendering conventional control ineffective. Here, we explore the use of homing suppression gene drive in fire ants by developing a spatially explicit model. Overall, these results show that target population suppression requires an extended time scale, but that gene ...
Yiran Liu   +3 more
wiley   +1 more source

MRI of Transgene Expression: Correlation to Therapeutic Gene Expression

open access: yesNeoplasia: An International Journal for Oncology Research, 2002
Magnetic resonance imaging (MRI) can provide highresolution 3D maps of structural and functional information, yet its use of mapping in vivo gene expression has only recently been explored.
Tomotsugu Ichikawa   +7 more
doaj   +1 more source

Early expression of a T-cell receptor beta-chain transgene suppresses rearrangement of the V gamma 4 gene segment. [PDF]

open access: green, 1988
Harald von Boehmer   +9 more
openalex   +1 more source

Muscle Organoids Reveal Exercise‐Like Contractions Rapidly Promote Muscle Health Via Lamtor1's Signaling to Both AMPK and mTOR

open access: yesAdvanced Science, EarlyView.
This study develops a novel 3D human skeletal muscle organoid platform to study the immediate molecular effects of exercise‐like contractions. The model uncovers rapid proteomic and transcriptomic responses, resolving a fundamental paradox by demonstrating how exercise‐induced Lamtor1 coordinately activates both AMPK and mTORC1. Lamtor1 is a compelling
Ziyue Yao   +9 more
wiley   +1 more source

In vivo evidence for NMDA receptor mediated excitotoxicity in a murine genetic model of Huntington Disease [PDF]

open access: yes, 2008
N-methyl-D-aspartate receptor (NMDAR) mediated excitotoxicity is implicated as a proximate cause of neurodegeneration in Huntington Disease (HD). However, this hypothesis has not been tested rigorously in vivo. NMDAR NR2B-subunits are the predominant NR2
Joe Tsien   +4 more
core   +1 more source

Transgenics on the internet [PDF]

open access: yesNature Biotechnology, 1997
Richard Peters, Robert S. Sikorski
openaire   +3 more sources

A Natural Major Module Confers the Trade‐Off between Phenotypic Mean and Plasticity of Grain Chalkiness in Rice

open access: yesAdvanced Science, EarlyView.
This study reveals the genetic and molecular mechanisms controlling the general trade‐off between phenotypic mean and plasticity of grain chalkiness in rice and identifies two major external drivers (high temperature and wide grain) and a natural major module (GCP6‐MPC5) that control this trade‐off.
Juncheng Zhang   +10 more
wiley   +1 more source

A dominant-negative transgene defines a role for p56lck in thymopoiesis. [PDF]

open access: bronze, 1993
Steven D. Levin   +3 more
openalex   +1 more source

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