Results 161 to 170 of about 176,088 (291)

Transfection of bovine fetal fibroblast with polyethylenimine (PEI) nanoparticles: effect of particle size and presence of fetal bovine serum on transgene delivery and cytotoxicity [PDF]

, 2017
Diego Oscar Forcato, A. E. Fili, Fabrisio Alustiza, Juan M. Lázaro‐Martínez, Silvestre Bongiovanni Abel, María Florencia Olmos Nicotra, A. P. Alessio, N. Rodríguez, César A. Barbero, Pablo Bosch   +9 more
openalex   +1 more source

Autophagy Plays a Suppressive Role in Bladder Tumor Formation in an Orthotopic Mouse Model and Bladder Cancer Patient Specimens

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Autophagy plays either a suppressing or promoting role during tumor development. Clarifying the role of autophagy in bladder tumorigenesis both in vitro and in vivo is crucial for developing novel therapeutic strategies through manipulating autophagy activity.
Wan‐Ting Kuo, Chin‐Chen Pan, Yi‐Wen Liu, Nan‐Haw Chow, Hong‐Lin Cheng, Shan‐Ying Wu, Sheng‐Hui Lan, Chih‐Peng Chang, Hsiao‐Sheng Liu   +8 more
wiley   +1 more source

Local administration of AAV-DJ pseudoserotype expressing COX2 provided early onset of transgene expression and promoted bone fracture healing in mice [PDF]

, 2015
Ram Lakhan, David J. Baylink, K.‐H. William Lau, Xiaolei Tang, Matilda H.‐C. Sheng, Charles H. Rundle, Xuezhong Qin   +6 more
openalex   +1 more source

Uncovering the Complexity of Synucleinopathies: An Ongoing Tale Between Proteins and Lipids

Movement Disorders, EarlyView.
Abstract Neurodegenerative diseases are pathological states characterized by progressive alterations in brain homeostasis during aging. Synucleinopathies, including Parkinson's disease and dementia with Lewy bodies, are defined neuropathologically by the accumulation of inclusions known as Lewy bodies and Lewy neurites.
Manuel Flores‐León, Tiago F. Outeiro
wiley   +1 more source

Human Genome Safe Harbor Sites: A Comprehensive Review of Criteria, Discovery, Features, and Applications. [PDF]

Cells
Ahmed A, Di Molfetta D, Iaconisi GN, Caponio A, Singh A, Bibi A, Dolce V, Palmieri L, Coppola V, Fiermonte G.   +9 more
europepmc   +1 more source

On the Use of Post-Transcriptional Processing Elements in Transgenes [PDF]

, 2004
Bruce Whitelaw, László Hiripi, Elena Farini, Margaret L. Opsahl, Zsuzsanna Bösze   +4 more
openalex   +1 more source

Modulation of the Stress Granule Component Carhsp1 Mitigates Disease‐Associated Deficits in Spinocerebellar Ataxia Type 3 Mouse Models

Movement Disorders, EarlyView.
Abstract Background Spinocerebellar ataxia type 3 (SCA3) is a polyglutamine (polyQ) neurogenerative disorder that results from CAG trinucleotide repeat expansions in the ATXN3 gene, leading to toxic protein aggregate formation and cellular pathway dysfunction.
Tiago Moreira‐Gomes, Adriana Marcelo, Ana Teresa Rajado, Rafael G. Costa, Ricardo Afonso‐Reis, Cristiana R. Madeira, Inês T. Afonso, David V.C. Brito, Adriana A. Vaz, Clévio Nóbrega   +9 more
wiley   +1 more source

Highly efficient gene editing via targeted Cas9 insertion into chicken housekeeping gene. [PDF]

Poult Sci
Jung KM, Klein R, Mony SI, Chen PR, Lee K, Lee HJ.   +5 more
europepmc   +1 more source

Systematic generation of Drosophila Wnt transgenes enables the characterization of canonical Wnt signaling

Jamie C Little, Marc Debrunner, Thom de Hoog, Farzad Tadjik, Chiara J. Kehl, George Hausmann, Erich Brunner, Konrad Basler   +7 more
openalex   +1 more source

Integrase-mediated, site-specific integration of transgenes in mice [PDF]

, 2011

openalex   +1 more source