Results 181 to 190 of about 227,142 (341)

Human CD8 transgene regulation of HLA recognition by murine T cells. [PDF]

, 1995
Drake LaFace, Mikael Vestberg, Yating Yang, Ratika Srivastava, James P. Di Santo, Neal Flomenberg, S Brown, Linda A. Sherman, P A Peterson   +8 more
openalex   +1 more source

Iterative hybrid model based optimization of rAAV production

Biotechnology Progress, EarlyView.
Abstract Changes in serotype or genetic payload of recombinant adeno associated virus (rAAVs) gene therapies require adapting the transfection conditions of the upstream HEK293 cultivations. This study adopts an iterative model‐based experiment design approach, where increasing data availability is leveraged to evolve models of different complexity ...
Claudio Müller, Gerald Siegwart, Susanne Heider, Michael Sokolov, Angela Botros, Alexandra Umprecht, Moritz von Stosch, Mariano Nicolas Cruz Bournazou   +7 more
wiley   +1 more source

SeedSeg: image-based transgenic seed counting for segregation analysis of T-DNA loci. [PDF]

Plant Methods
Hernández S, Zhong V, Brophy JAN.
europepmc   +1 more source

Stochastic, stage-specific mechanisms account for the variegation of a human globin transgene [PDF]

, 1998
Timothy A. Graubert, Bruce A. Hug, Robin L. Wesselschmidt, Chih‐Lin Hsieh, Thomas M. Ryan, Timothy M Townes, Timothy J. Ley   +6 more
openalex   +1 more source

Accelerating AAV purification process development using high‐throughput resin tip module

Biotechnology Progress, EarlyView.
Abstract Recombinant adeno‐associated viruses (AAVs) with precise genome editing and cell‐virus interaction have become a promising delivery tool for gene therapy. A robust AAV purification process is crucial for ensuring therapeutic efficacy. The challenges of AAV purification process development encompass limited material availability during early ...
Qingxuan Li, Mahsa Hadidi, Steven Benner, Junfen Ma   +3 more
wiley   +1 more source

Pollen Quantitative and Genetic Competitiveness of Rice (<i>Oryza sativa</i> L.) and Their Effects on Gene Flow. [PDF]

Plants (Basel)
Hu N, Wang D, Yuan Q, Liu Y, Jiang H, Pei X.   +5 more
europepmc   +1 more source

Microinjection of Cre recombinase RNA induces site-specific recombination of a transgene in mouse oocytes [PDF]

, 1998
Thijs de Wit, Dubravka Drabek, Frank Grosveld   +2 more
openalex   +1 more source

An RNA-Dependent RNA Polymerase Gene in Arabidopsis Is Required for Posttranscriptional Gene Silencing Mediated by a Transgene but Not by a Virus

Cell, 2000
T. Dalmay, A. Hamilton, S. Rudd, S. Angell, D. Baulcombe   +4 more
semanticscholar   +1 more source

Transgene Mapping in Animals: What to Choose? [PDF]

Int J Mol Sci
Smirnov A, Makarenko M, Yunusova A.
europepmc   +1 more source

Spatiotemporal control of gene expression by a light-switchable transgene system

Nature Methods, 2012
Xue Wang, Xianjun Chen, Yi Yang
semanticscholar   +1 more source