Results 211 to 220 of about 360,625 (378)
Myomaker and Myomixer are required for craniofacial myoblast fusion in zebrafish
Abstract Background Craniofacial and trunk skeletal muscles are derived from different progenitor populations during development. Trunk skeletal muscles contain mostly multinucleated myofibers that are formed through myoblast fusion. However, myoblast fusion in craniofacial muscles and its molecular regulation are not well understood.
Zhanxiong Zhang +3 more
wiley +1 more source
Human Genome Safe Harbor Sites: A Comprehensive Review of Criteria, Discovery, Features, and Applications. [PDF]
Ahmed A +9 more
europepmc +1 more source
An inducible transgene expression system for regulated phenotypic modification of human embryonic stem cells [PDF]
Ji‐Dong Fu, Camie W. Chan, Ronald A Li
openalex +1 more source
Abstract Background Robinow syndrome is a rare developmental syndrome caused by variants in genes in Wnt signaling pathways. We previously showed that expression of patient variants in Dishevelled 1 (DVL1) in Drosophila and chicken models disrupts the balance of canonical and non‐canonical Wnt signaling.
Gamze Akarsu +4 more
wiley +1 more source
AAV Gene Therapy Drug Development and Translation of Engineered Ocular and Neurotropic Capsids: A Systematic Review Using Natural Language Processing. [PDF]
Agbim C +5 more
europepmc +1 more source
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff +6 more
wiley +1 more source
Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology
Abstract Maternal effects, encompassing both genetic (maternally expressed gene products) and non‐genetic (maternal state) influences, are powerful determinants of offspring phenotype, yet their RNA‐level mechanisms remain incompletely resolved. In parallel, epitranscriptomics, an emerging field centered on chemical modifications to RNA, has revealed ...
Ehsan Pashay Ahi
wiley +1 more source
The Cold Case Files of rAAV Capsid Influence on Transduction: New Leads. [PDF]
Powell SK.
europepmc +1 more source

