Results 241 to 250 of about 227,142 (341)

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Genome editing for sustainable agriculture in Peru: advances, potential applications and regulation. [PDF]

Front Genome Ed
Mestanza M, Hernández-Amasifuen AD, Pineda-Lázaro AJ, Eriksson D, Guerrero-Abad JC.   +4 more
europepmc   +1 more source

Efficient Conditional Transgene Expression in Hepatitis C Virus cDNA Transgenic Mice Mediated by the Cre/loxP System [PDF]

, 1998
Takaji Wakita, Choji Taya, Asao Katsume, Junko Katô, Hiromichi Yonekawa, Yumi Kanegae, Izumu Saito, Yukiko Hayashi, Morio Koike, Michinori Kohara   +9 more
openalex   +1 more source

Overexpression of TSG101 causes the development of adenosquamous mammary carcinoma. [PDF]

Breast Cancer Res
Dennaoui R, Rädler PD, Wicker MN, Vistisen K, Ferraiuolo RM, Triplett AA, Shrestha H, Liner TA, Manthey KC, Rui H, Cardiff RD, Gunn TM, Perou CM, Wagner KU.   +13 more
europepmc   +1 more source

Mouse mammary tumor virus/v-Ha- ras transgene-induced mammary tumors exhibit strain-specific allelic loss on mouse chromosome 4

, 1997
Eric H. Radany, Karen Hong, Sima Kesharvarzi, Eric S. Lander, J. Michael Bishop   +4 more
openalex   +1 more source

Efficient Liver-specific Deletion of a Floxed Human Angiotensinogen Transgene by Adenoviral Delivery of Cre Recombinasein Vivo [PDF]

, 1999
David E. Stec, Robin L. Davisson, Ronald E. Haskell, Beverly L. Davidson, Curt D. Sigmund   +4 more
openalex   +1 more source

Retracted: Viral pathogenicity determinants are suppressors of transgene silencing in Nicotiana benthamiana

EMBO Journal, 1998
G. Brigneti, O. Voinnet, Wanxiang Li, Liang‐Hui Ji, S. Ding, D. Baulcombe   +5 more
semanticscholar   +1 more source

Diverse Subpopulations of Reactive Astrocytes Following Chronic Toxoplasma Infection

Glia, EarlyView.
Toxoplasma infection results in distinct astrocyte subpopulations. Chronically labeled reactive astrocytes appear transcriptionally plastic and can regain acute inflammatory responding and naive homeostatic astrocytic gene patterns in the presence of ongoing neuroinflammation.
Zoe A. Figueroa, Jose L. Martin, Arzu Ulu, William Agnew‐Svoboda, Teresa Ubina, Martin M. Riccomagno, Todd A. Fiacco, Emma H. Wilson   +7 more
wiley   +1 more source

Development and Characterization of the NISTCHO Reference Cell Line. [PDF]

Biotechnol J
Dahodwala H, Hodzic I, Slesarev A, Cutak B, Kuzin A, Lal R, Liu J, Mahon J, Narasimhan RL, Onuska J, Ravellette J, Reger K, Sakurada S, Stewart F, Borgschulte T, Cote C, Lee KH, O'Dell WB, Kelman Z, Anderson BA.   +19 more
europepmc   +1 more source

Specific expression in mouse mesoderm- and neural crest-derived tissues of a human PDGFRA promoter/lacZ transgene

, 1998
Xiaoqun Zhang, Gijs Afink, Kristian Svensson, Jacqueline J.L. Jacobs, Thomas Günther, Karin Forsberg‐Nilsson, E.J.J. van Zoelen, Bengt Westermark, Monica Nistér   +8 more
openalex   +1 more source