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Current Status of Clinical Gene Therapy for Hemophilia and Globin Disorders. [PDF]
Winkler R +5 more
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Engineering Liver-Specific Promoters: A Comprehensive Review of Design, Mechanisms, and Clinical Applications in Gene Therapy. [PDF]
Artemyev V +9 more
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Selective vulnerability of the aging cholinergic system to amyloid pathology revealed by induced APP overexpression. [PDF]
Xie K +6 more
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Trends in Biotechnology, 1990
A range of transgenic animal species have been generated using DNA microinjection, and application of this technique to fish is now showing some degree of success. Studies to optimize microinjection techniques specifically for use with fish, and to investigate possible alternative methods for mass culture, should lead to the commercial production of ...
T T, Chen, D A, Powers
openaire +2 more sources
A range of transgenic animal species have been generated using DNA microinjection, and application of this technique to fish is now showing some degree of success. Studies to optimize microinjection techniques specifically for use with fish, and to investigate possible alternative methods for mass culture, should lead to the commercial production of ...
T T, Chen, D A, Powers
openaire +2 more sources
International Journal of Biochemistry, 1994
1. Although many human therapeutic proteins are currently produced in microbial fermentors using recombinant DNA techniques, it is obvious that microbial processing is not suitable for a large number of bioactive proteins owing to the inability of bacteria to carry out postsynthetic modification reactions required for full biological activity. 2.
J, Jänne +6 more
openaire +2 more sources
1. Although many human therapeutic proteins are currently produced in microbial fermentors using recombinant DNA techniques, it is obvious that microbial processing is not suitable for a large number of bioactive proteins owing to the inability of bacteria to carry out postsynthetic modification reactions required for full biological activity. 2.
J, Jänne +6 more
openaire +2 more sources
2014
Transgenic resistance to plant viruses is an important technology for control of plant virus infection, which has been demonstrated for many model systems, as well as for the most important plant viruses, in terms of the costs of crop losses to disease, and also for many other plant viruses infecting various fruits and vegetables.
Cillo Fabrizio, Palukaitis Peter
openaire +3 more sources
Transgenic resistance to plant viruses is an important technology for control of plant virus infection, which has been demonstrated for many model systems, as well as for the most important plant viruses, in terms of the costs of crop losses to disease, and also for many other plant viruses infecting various fruits and vegetables.
Cillo Fabrizio, Palukaitis Peter
openaire +3 more sources
British Veterinary Journal, 1994
The ability to manipulate the genome of the whole animal has, for the past 10 years, provided researchers with an alternative route of inquiry into many complex biological processes. Transgenic animals have numerous applications, encompassing a wide range of different disciplines, but they have proved especially useful in the investigation of gene ...
E R, Cameron, M J, Harvey, D E, Onions
openaire +2 more sources
The ability to manipulate the genome of the whole animal has, for the past 10 years, provided researchers with an alternative route of inquiry into many complex biological processes. Transgenic animals have numerous applications, encompassing a wide range of different disciplines, but they have proved especially useful in the investigation of gene ...
E R, Cameron, M J, Harvey, D E, Onions
openaire +2 more sources

