933. Sendai Virus Vector Can Efficiently Introduce Transgene into Cardiomyocytes In Vitro and In Vivo [PDF]
openalex +1 more source
Hemophilia A: An Ideal Disease for Prenatal Therapy
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada +2 more
wiley +1 more source
Emerging Technologies Tackling Adeno-Associated Viruses (AAV) Immunogenicity in Gene Therapy Applications. [PDF]
Egorova T, Starikova A, Polikarpova A.
europepmc +1 more source
475. Functional Redundancy of Immunomodulatory Genes: Potent Protective Immunity Is Induced Against Pseudomonas Aeruginosa through Immunization with Antigen-Pulsed Dendritic Cells Genetically Modified with Different Immunomodulatory Transgenes [PDF]
openalex +1 more source
Engineering compact Physalis peruviana (goldenberry) to promote its potential as a global crop
Goldenberry (Physalis peruviana) produces sweet, nutritionally rich berries, yet like many minor crops, is cultivated in limited geographical regions and has not been a focus of breeding programs for trait enhancement. Leveraging knowledge of plant architecture‐related traits from related species, we used CRISPR/Cas9‐mediated gene editing to generate a
Miguel Santo Domingo +8 more
wiley +1 more source
Development of a high-yield Rabbit line for enhanced animal pharming. [PDF]
Song J +7 more
europepmc +1 more source
Transport engineering as a strategy to realize rapeseed's potential as a protein‐rich food
The heavily pesticide‐dependent rapeseed is an under‐utilized protein source for food owing to anti‐nutritional glucosinolates. Transport engineering technology may reduce glucosinolates in seeds while increasing defense in vegetative parts. Abstract Rapeseed is the world's second‐largest oilseed crop, and the low‐value press cake that remains after ...
Jakob Skytte Thorsen +2 more
wiley +1 more source
Double-strand break-free and transgene-free genome editing in the microalga Nannochloropsis oceanica using removable vectors containing the CRISPR base editing system. [PDF]
Moroi K, Yamamoto T, Kurita T.
europepmc +1 more source

