Results 281 to 290 of about 360,625 (378)

Aberrant RNA identification reveals triggers of transgene silencing. [PDF]

Plant Cell
Willoughby AC.
europepmc   +1 more source

Regulation of the Target Protein (Transgene) Expression in the Adenovirus Vector Using Agonists of Toll-Like Receptors

, 2014
Alexander Bagaev, Pichugin Av, Е.С. Лебедева, А. А. Лысенко, М. М. Шмаров, Denis Y. Logunov, Boris S. Naroditsky, Ravshan Ataullakhanov, Rakhim M. Khaitov, Gintsburg Al   +9 more
openalex   +1 more source

The transformer gene controls sexual development in Drosophila suzukii

Insect Science, EarlyView.
The transformer gene plays a key role in the genetic pathway for sexual development in Drosophila suzukii Abstract The genetic network of sex determination in the model organism Drosophila melanogaster was investigated in great detail. Such knowledge not only advances our understanding of the evolution and regulation of sexual dimorphism in insects ...
Ying Yan, Jing Zhao, Jonas Schwirz, Cristina Borghesi, Conghui Liu, Bo Liu, Wanqiang Qian, Fanghao Wan, Marc F. Schetelig   +8 more
wiley   +1 more source

Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells

Nature Biotechnology, 2011
E. Papapetrou, Gabsang Lee, N. Malani, M. Setty, I. Rivière, Laxmi MS Tirunagari, K. Kadota, Shoshannah L. Roth, P. Giardina, A. Viale, C. Leslie, F. Bushman, L. Studer, M. Sadelain   +13 more
semanticscholar   +1 more source

Genetic engineering for SIT application: a fruit fly‐focused review

Insect Science, EarlyView.
Abstract Sterile insect technique (SIT) has become a key component of efficient pest control. Fruit fly pests from the Drosophilidae and Tephritidae families pose a substantial and overwhelmingly increasing threat to the agricultural industry, aggravated by climate change and globalization among other contributors.
Serafima Davydova, Danheng Yu, Angela Meccariello   +2 more
wiley   +1 more source

Regulation of therapeutic protein release in response to circadian biomarkers. [PDF]

Nat Commun
Franko N, Li S, Galvan S, Csorba Z, Teixeira AP, Xie M, Fussenegger M.   +6 more
europepmc   +1 more source

Generation of Transgene‐Free Lung Disease‐Specific Human Induced Pluripotent Stem Cells Using a Single Excisable Lentiviral Stem Cell Cassette

Stem Cells, 2010
A. Somers, J. Jean, C. Sommer, Amel Omari, Christopher C. Ford, J. Mills, Lei Ying, A. G. Sommer, Jenny M. Jean, Brenden W. Smith, R. Lafyatis, M. Demierre, Daniel J. Weiss, Deborah L. French, Paul Gadue, George J. Murphy, G. Mostoslavsky, D. Kotton   +17 more
semanticscholar   +1 more source

Functional validation of a white pupae minimal gene construct in Ceratitis capitata (Diptera: Tephritidae)

Insect Science, EarlyView.
An intronless version of the white pupae (wp) gene was engineered to restore the wild type brown puparium color in white pupae phenotype mutants of the Mediterranean fruit fly, Ceratitis capitata. Functionality of the minimal gene version (mini‐wp) was verified in vivo, as one copy of mini‐wp successfully restored the wild type phenotype in homozygous ...
Lucas Henrique Figueiredo Prates, Roswitha A. Aumann, Inga Sievers, Tanja Rehling, Marc F. Schetelig   +4 more
wiley   +1 more source

A Longitudinal 3D Live-Cell Imaging Platform to Uncover AAV Vector-Host Dynamics at Single-Cell Resolution. [PDF]

Int J Mol Sci
Leysen M, Peredo N, Pavie B, Moeyaert B, Henckaerts E.   +4 more
europepmc   +1 more source

Maltase 1 regulates DENV2 infection and life history in Aedes aegypti

Insect Science, EarlyView.
Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li, Jin Cheng, Ya‐Ming Zou, Quan‐Chao Liu, Ding Zhu, Ce‐Jie Lan   +5 more
wiley   +1 more source