Results 291 to 300 of about 293,415 (335)

Nonclinical strategies and considerations to enable the redosing of gene therapies. [PDF]

Mol Ther Methods Clin Dev
Moffit JS, Alatsis KR, Blanset DL, Buss N, Rana P.   +4 more
europepmc   +1 more source

Economic Impact of Severe Early‐Onset Foetal Growth Restriction: A Multicentre Prospective Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Foetal growth restriction (FGR) affects 10% of pregnancies, contributing to 30% of stillbirths. Current management of early‐onset FGR (< 32 + 0 weeks' gestation) delivers the foetus before stillbirth or irreversible organ damage. The resulting preterm births create additional risks independent of FGR.
George Bray, Kasia Maksym, Maurvi Dilipkumar, Rebecca N. Spencer, Yuval Ginsberg, Tal Weissbach, Donald M. Peebles, Neil Marlow, Angela Huertas‐Ceballos, Gina Buquis, Jade Okell, Kurt Hecher, Anke Diemert, Dominique Singer, Stefan R. Hansson, David Ley, Francesc Figueras, Eduard Gratacós, Fatima Crispi, Anna L. David, Rachael Hunter   +20 more
wiley   +1 more source

Regulation of MORC-1 is key to the CSR-1-mediated germline gene licensing mechanism in <i>C. elegans</i>. [PDF]

Sci Adv
Kirshner JA, Picard CL, Weiser NE, Mehta N, Feng S, Murphy VN, Vakhnovetsky A, Alessi AF, Xiao C, Inoki K, El Mouridi S, Frøkjær-Jensen C, Jacobsen SE, Kim JK.   +13 more
europepmc   +1 more source

Evaluation of two candidate molecules—TCTP and cecropin—on the establishment of Trypanosoma brucei gambiense into the gut of Glossina palpalis gambiensis

Insect Science, EarlyView.
This study investigates the potential of enhancing the resistance of Glossina palpalis gambiensis to Trypanosoma brucei gambiense to mitigate the transmission of Human African Trypanosomiasis. We successfully cloned genes encoding proteins of interest in Sodalis strains, resulting in recombinant Sodalis (recSodalis) that were micro‐injected into the L3
François Sougal Ngambia Freitas, Linda De Vooght, Flobert Njiokou, Jan Van Den Abeele, Géraldine Bossard, Bernadette Tchicaya, Rosa Milagros Corrales, Sophie Ravel, Anne Geiger, David Berthier‐Teyssedre   +9 more
wiley   +1 more source

Synthetic feed-forward loop circuit boosts transgene expression in sugarcane. [PDF]

Plant Cell Rep
Zhang Z, Anwar S, Yafuso EJ, Zuniga Soto ET, Li C, Luo G, Moose SP, Swaminathan K, Altpeter F, Hudson ME.   +9 more
europepmc   +1 more source

The transformer gene controls sexual development in Drosophila suzukii

Insect Science, EarlyView.
The transformer gene plays a key role in the genetic pathway for sexual development in Drosophila suzukii Abstract The genetic network of sex determination in the model organism Drosophila melanogaster was investigated in great detail. Such knowledge not only advances our understanding of the evolution and regulation of sexual dimorphism in insects ...
Ying Yan, Jing Zhao, Jonas Schwirz, Cristina Borghesi, Conghui Liu, Bo Liu, Wanqiang Qian, Fanghao Wan, Marc F. Schetelig   +8 more
wiley   +1 more source

Crash-and-dash: a new era in tree genome editing. [PDF]

New Phytol
Tsai CJ.
europepmc   +1 more source

Functional validation of a white pupae minimal gene construct in Ceratitis capitata (Diptera: Tephritidae)

Insect Science, EarlyView.
An intronless version of the white pupae (wp) gene was engineered to restore the wild type brown puparium color in white pupae phenotype mutants of the Mediterranean fruit fly, Ceratitis capitata. Functionality of the minimal gene version (mini‐wp) was verified in vivo, as one copy of mini‐wp successfully restored the wild type phenotype in homozygous ...
Lucas Henrique Figueiredo Prates, Roswitha A. Aumann, Inga Sievers, Tanja Rehling, Marc F. Schetelig   +4 more
wiley   +1 more source

Promoter replacement by genome editing creates gain-of-function traits in Arabidopsis. [PDF]

Plant Biotechnol J
Nobusawa T, Nakano M, Nagashima Y, Kusaba M.   +3 more
europepmc   +1 more source

The insulin-like peptide INS-27 mediates a muscle-to-neuron feedback signal coupling muscle activity with AMPA receptor trafficking. [PDF]

PLoS Genet
Rennich BJ, Powers RM, Moores S, Hodul M, Juo P.   +4 more
europepmc   +1 more source